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Titolo:
QT dispersion in patients with mitral valve prolapse is related to the echocardiographic degree of the prolapse and mitral leaflet thickness
Autore:
Zouridakis, EG; Parthenakis, FI; Kochiadakis, GE; Kanoupakis, EM; Vardas, PE;
Indirizzi:
Univ Hosp Heraklion, Dept Cardiol, Iraklion, Greece Univ Hosp Heraklion Iraklion Greece ion, Dept Cardiol, Iraklion, Greece
Titolo Testata:
EUROPACE
fascicolo: 4, volume: 3, anno: 2001,
pagine: 292 - 298
SICI:
1099-5129(200110)3:4<292:QDIPWM>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMA-CATECHOLAMINE LEVELS; PAPILLARY-MUSCLE TRACTION; TERM FOLLOW-UP; VENTRICULAR ARRHYTHMIAS; INTERVAL DISPERSION; SUDDEN-DEATH; REPOLARIZATION; QUANTITATION; HEART; REFRACTORINESS;
Keywords:
mitral valve prolapse; QT dispersion.; echocardiographic degree of prolapse;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Vardas, PE Univ Hosp Heraklion, Dept Cardiol, POB 1532, Iraklion, Greece Univ Hosp Heraklion POB 1532 Iraklion Greece Iraklion, Greece
Citazione:
E.G. Zouridakis et al., "QT dispersion in patients with mitral valve prolapse is related to the echocardiographic degree of the prolapse and mitral leaflet thickness", EUROPACE, 3(4), 2001, pp. 292-298

Abstract

Background Ventricular arrhythmias are common in patients with mitral valve prolapse (MVP). Previous studies have provided evidence that a higher degree of systolic mitral valve displacement and the presence of a thickened anterior mitral leaflet are related to an increased incidence of complex ventricular arrhythmias and risk of sudden death in these patients. The aim ofour study was to investigate whether QT dispersion in patients with MVP isassociated with the echocardiographic degree of the prolapse and mitral leaflet thickness. Methods QT and JT intervals and dispersions were measured in 89 patients with primary mitral valve prolapse (26 men and 63 women with mean age 39 +/-14 years). All patients underwent a full echocardiographic examination anda scoring system was used to determine the degree of MVP. Anterior mitral leaflet thickness was also measured. Twenty-four hour Holter monitoring wasused to assess ventricular arrhythmogenesis. Results According to their echocardiographic score, patients were divided into three groups (Group A, B and C) reflecting the different degrees of the prolapse. QT dispersion in patients with the highest degree of MVP, i.e. Group C was significantly greater (65 +/- 13 ms) than that of the other twogroups (Group A: 38 +/- 14 ms, P < 0.005 and Group B: 45 +/- 12 ms, P < 0.005). Similar differences between groups were also found for JT dispersion. Multiple regression analysis revealed that among the demographic and clinical variables that were tested, only the echocardiographic degree of the prolapse and anterior mitral leaflet thickness were independently associated with QT dispersion. Holler monitoring showed that the incidence of complex ventricular arrhythmias was also higher in patients with more severe MVP. Conclusions Our results indicate that QT and JT dispersions are related tothe echocardiographic degree of MVP and mitral leaflet thickness. The echocardiographic assessment of the severity of the prolapse may help to identify a subgroup of patients at increased risk of life-threatening arrhythmias. (C) 2001 The European Society of Cardiology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 10:33:38