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Titolo:
New aspects of Wnt signaling pathways in higher vertebrates
Autore:
Huelsken, J; Birchmeier, W;
Indirizzi:
Max Delbruck Ctr Mol Med, D-13092 Berlin, Germany Max Delbruck Ctr Mol Med Berlin Germany D-13092 D-13092 Berlin, Germany
Titolo Testata:
CURRENT OPINION IN GENETICS & DEVELOPMENT
fascicolo: 5, volume: 11, anno: 2001,
pagine: 547 - 553
SICI:
0959-437X(200110)11:5<547:NAOWSP>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONVERGENT EXTENSION MOVEMENTS; ANTERIOR-POSTERIOR AXIS; BETA-CATENIN; STEM-CELLS; XENOPUS EMBRYOS; CAENORHABDITIS-ELEGANS; FUNCTIONAL INTERACTION; GENOME SEQUENCE; C-ELEGANS; MICE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
83
Recensione:
Indirizzi per estratti:
Indirizzo: Birchmeier, W Max Delbruck Ctr Mol Med, Robert Rossle Str 10, D-13092 Berlin, Germany Max Delbruck Ctr Mol Med Robert Rossle Str 10 Berlin Germany D-13092
Citazione:
J. Huelsken e W. Birchmeier, "New aspects of Wnt signaling pathways in higher vertebrates", CUR OP GEN, 11(5), 2001, pp. 547-553

Abstract

The development of tissues and organs in embryos is controlled by an interplay of several signaling pathways that cross-talk to provide positional information and induce cell fate specification. One of the major signaling systems is the Writ pathway which was recently shown to split into several intracellular branches which regulate multiple cellular functions. In the present review, we discuss novel members and their role in the diversificationof the Writ pathway. Many of these components were studied in model organisms such as C. elegans, Drosophila and Xenopus. Here we focus on recent studies of mutant phenotypes in Mouse and Zebrafish which implicate members ofthe Writ pathway in processes such as axis and mesoderm formation, initiation of organ development and stem cell differentiation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 08:21:35