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Titolo:
Genetics of Epstein-Barr virus infection
Autore:
Hiraki, A; Fujii, N; Masuda, K; Ikeda, K; Tanimoto, M;
Indirizzi:
Okayama Univ, Sch Med, Dept Med 2, Okayama 7008558, Japan Okayama Univ Okayama Japan 7008558 d, Dept Med 2, Okayama 7008558, Japan
Titolo Testata:
BIOMEDICINE & PHARMACOTHERAPY
fascicolo: 7, volume: 55, anno: 2001,
pagine: 369 - 372
SICI:
0753-3322(200109)55:7<369:GOEVI>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
EPITHELIAL-CELLS; MONONUCLEAR-CELLS; EBV PERSISTENCE; LYMPHOCYTES-B; CARRIER STATE; PROTEIN LMP1; REPLICATION; LYMPHOMA; LATENCY; EXPRESSION;
Keywords:
Epstein-Barr virus; immune response; latent infection; replication;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Hiraki, A Okayama Univ, Sch Med, Dept Med 2, 2-5-1 Shikata Cho, Okayama 7008558, Japan Okayama Univ 2-5-1 Shikata Cho Okayama Japan 7008558 558, Japan
Citazione:
A. Hiraki et al., "Genetics of Epstein-Barr virus infection", BIOMED PHAR, 55(7), 2001, pp. 369-372

Abstract

Epstein-Barr (EBV) virus is a member of the human herpesvirus family. EBV is the etiologic agent of acute infectious mononucleosis and is closely associated with the genesis of Burkitt's lymphoma and undifferentiated nasopharyngeal carcinoma. EBV is also implicated in a variety of other diseases, such as X-linked lymphoproliferative syndrome, T-cell non-Hodgkin's lymphoma, Hodgkin's disease, and NK-cell granular lymphoproliferative disorder. Recently, lymphoepithelial carcinoma of the stomach, gastric carcinoma, pyothorax-associated lymphoma, and smooth muscle tumors were also recognized as EBV-associated diseases. It is therefore important to review the genetics and immunological response of EBV infection. In this review we summarize the genetics of EBV, immunological responses and clinical findings of EBV-associated diseases, which would help us to understand the pathophysiology of EBV-associated disease and develop specific treatments. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 19:54:06