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Titolo:
Light exposure and the risk of age-related macular degeneration - The Pathologies Oculaires Liees a l'Age (POLA) study
Autore:
Delcourt, C; Carriere, I; Ponton-Sanchez, A; Fourrey, S; Lacroux, A; Papoz, L;
Indirizzi:
INSERM U500, F-34093 Montpellier 5, France INSERM U500 Montpellier France 5 ERM U500, F-34093 Montpellier 5, France
Titolo Testata:
ARCHIVES OF OPHTHALMOLOGY
fascicolo: 10, volume: 119, anno: 2001,
pagine: 1463 - 1468
SICI:
0003-9950(200110)119:10<1463:LEATRO>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
BEAVER DAM EYE; POSTERIOR SUBCAPSULAR CATARACTS; BLUE-MOUNTAINS EYE; APOLIPOPROTEIN-E; LENS OPACITIES; MACULOPATHY; PREVALENCE; SUNLIGHT; ROTTERDAM; SMOKING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Delcourt, C INSERM U500, 39 Ave Charles Flahault, F-34093 Montpellier 5, France INSERM U500 39 Ave Charles Flahault Montpellier France 5 ance
Citazione:
C. Delcourt et al., "Light exposure and the risk of age-related macular degeneration - The Pathologies Oculaires Liees a l'Age (POLA) study", ARCH OPHTH, 119(10), 2001, pp. 1463-1468

Abstract

Background: The role of light exposure in the development of age-related macular degeneration (ARMD) has been questioned. We present the relationshipbetween lifetime light exposure and ARMD as examined in the Pathologies Oculaires Liees l'Age (POLA) study. Methods: The POLA study is a population-based study on cataract and ARMD and their risk factors. It included 2584 residents of the town of Sete, located in the South of France. The presence of early and late ARMD was assessed on the basis of 50 degrees color fundus photographs using an international classification system. A questionnaire about light exposure was administered. Results: Late ARMD (n = 38) was not significantly associated with any light exposure variable. Subjects exposed to high ambient solar radiation and those with frequent leisure exposure to sunlight had a decreased risk of pigmentary abnormalities (odds ratio [OR] = 0.61; 95% confidence interval [CI], 0.39-0.93, and OR= 0.70; 95% CI, 0.52-0.95, respectively) and of early signs of ARMD (OR=0.73; 95% CI, 0.54-0.98, and OR=0.80; 95% CI, 0.64-1.00, respectively). Subjects who had used sunglasses regularly had a decreased risk of soft drusen (OR=0.81; 95% CI, 0.66-1.00). These relationships were notmodified by further adjustments for potential confounders. Conclusion: Our study does not support a deleterious effect of sunlight exposure in ARMD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 15:11:03