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Titolo:
Adherence to highly active antiretroviral therapy in the real world: experience of twelve English HIV units
Autore:
Brook, MG; Dale, A; Tomlinson, D; Waterworth, C; Daniels, D; Forster, G;
Indirizzi:
Cent Middlesex Hosp, Patrick Clements Clin, London NW10 7NS, England Cent Middlesex Hosp London England NW10 7NS in, London NW10 7NS, England Camden & Islington Community Hlth Serv NHS Trust, Clin Governance Support Unit, London, England Camden & Islington Community Hlth Serv NHS Trust London England England St Marys Hosp, Imperial Coll, Dept Genitourinary HIV Med, London, England St Marys Hosp London England ept Genitourinary HIV Med, London, England Tower Hamlets Hlth Author, London, England Tower Hamlets Hlth Author London England s Hlth Author, London, England W Middlesex Univ Hosp, Dept GU Med, Isleworth, Middx, England W Middlesex Univ Hosp Isleworth Middx England Isleworth, Middx, England Royal London Hosp, Ambrose King Ctr, London E1 1BB, England Royal London Hosp London England E1 1BB King Ctr, London E1 1BB, England
Titolo Testata:
AIDS PATIENT CARE AND STDS
fascicolo: 9, volume: 15, anno: 2001,
pagine: 491 - 494
SICI:
1087-2914(200109)15:9<491:ATHAAT>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROTEASE INHIBITOR THERAPY; SELF-REPORTED ADHERENCE; COMBINATION THERAPY; PREDICTORS; REGIMENS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Brook, MG Cent Middlesex Hosp, Patrick Clements Clin, Acton Lane, London NW10 7NS, England Cent Middlesex Hosp Acton Lane London England NW10 7NS England
Citazione:
M.G. Brook et al., "Adherence to highly active antiretroviral therapy in the real world: experience of twelve English HIV units", AIDS PAT CA, 15(9), 2001, pp. 491-494

Abstract

In order to describe how human immunodeficiency virus (HIV) clinics in andaround London are trying to optimize their patients' adherence to highly active antiretroviral therapy (HAART), we performed a survey of practice andpolicy in the clinics using a postal questionnaire. Clinics were also asked to review up to 10 randomly selected case notes of patients receiving HAART and complete a questionnaire on each about how adherence was encouraged and assessed. Twelve clinics took part in the project and surveyed the notes of 89 patients. The results show that several clinics define adequate adherence as taking more than 95% of prescribed doses although there was no uniform definition across the participating units. Adherence was encouraged through simplifying HAART regimens, providing dose-dispensing boxes and alarms, arranging early follow-up for patients starting treatment, and offeringcontinuing support through specific health care workers. Adequate discussion and provision of written information was seen as an important aid to adherence but the case note survey showed evidence of deficiencies in this area in approximately 40% of patients. Assessed levels of adherence were less than 95% in 27% of patients. The main reasons for suboptimal adherence werefound to be lack of motivation to take treatment by the patients, high pill burden, and drug side effects although there were several other contributing factors. This study shows that the HIV units take HAART adherence seriously but there are several deficiencies in putting policy into practice.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 10:58:54