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Titolo:
The effect of a combination of medetomidine-butorphanol and medetomidine, butorphanol, atropine on glomerular filtration rate in dogs
Autore:
Grimm, JB; Grimm, KA; Kneller, SK; Tranquilli, WJ; Crochik, SS; Bischoff, MG; Podolski, JL;
Indirizzi:
Univ Illinois, Coll Vet Med, Large Anim Clin, Dept Vet Clin Med, Urbana, IL 61802 USA Univ Illinois Urbana IL USA 61802 Dept Vet Clin Med, Urbana, IL 61802 USA
Titolo Testata:
VETERINARY RADIOLOGY & ULTRASOUND
fascicolo: 5, volume: 42, anno: 2001,
pagine: 458 - 462
SICI:
1058-8183(200109/10)42:5<458:TEOACO>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
TC-99M-DIETHYLENETRIAMINEPENTAACETIC ACID; TC-99M-DTPA; CATS;
Keywords:
glomerular filtration rate; nuclear scintigraphy; medetomidine; renal physiology; dogs;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Grimm, JB Univ Illinois, Coll Vet Med, Large Anim Clin, Dept Vet Clin Med,1008 W Hazelwood Dr, Urbana, IL 61802 USA Univ Illinois 1008 W Hazelwood Dr Urbana IL USA 61802 61802 USA
Citazione:
J.B. Grimm et al., "The effect of a combination of medetomidine-butorphanol and medetomidine, butorphanol, atropine on glomerular filtration rate in dogs", VET RAD ULT, 42(5), 2001, pp. 458-462

Abstract

The effects of intramuscularly administered medetomidine and butorphanol (MB), and medetomidine, butorphanol, atropine (MBA) on glomerular filtrationrate (GFR) were determined in six dogs as measured by 99m-Tc-labeled diethylenetriaminepentaacetic acid (Tc-99m-DTPA) nuclear scintigraphy. Direct systolic, diastolic, and mean arterial blood pressures and heart rate were measured at regular time intervals before, during, and after GFR calculations. The mean GFR measurement following MB was significantly greater (4.44 ml/min/kg) than following MBA (3.82 ml/min/kg) or saline treatment (3.41 ml/min/kg). There was no significant difference between the mean GFR measurements following MBA injection and following saline injection. Diastolic and mean arterial pressures following MBA injection were significantly higher thanthe values recorded after either MB or saline alone. Heart rate following NIB administration was significantly lower than that recorded for dogs receiving MBA or saline alone. The results of this study indicate that the administration of medetomidine in combination with butorphanol significantly increases total GFR in healthy dogs, while the administration of the combination of medetomidine, butorphanol, and atropine does not.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 19:43:38