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Titolo:
Intra-axial dermoid/epidermoid tumors of the brainstem in children
Autore:
Caldarelli, M; Colosimo, C; Di Rocco, C;
Indirizzi:
Univ Sacred Heart, Sch Med, Sect Pediat Neurosurg, Dept Neurosurg, I-00168Rome, Italy Univ Sacred Heart Rome Italy I-00168 Dept Neurosurg, I-00168Rome, Italy Univ Sacred Heart, Sch Med, Dept Radiol, I-00168 Rome, Italy Univ Sacred Heart Rome Italy I-00168 d, Dept Radiol, I-00168 Rome, Italy
Titolo Testata:
SURGICAL NEUROLOGY
fascicolo: 2, volume: 56, anno: 2001,
pagine: 97 - 105
SICI:
0090-3019(200108)56:2<97:IDTOTB>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
STEM EPIDERMOID CYST; POSTERIOR-FOSSA; DERMOID CYST; MR; VENTRICLE;
Keywords:
brain stem tumour; dermoid cysts; epidermoid cysts; MRI; surgical treatment;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Caldarelli, M Univ Sacred Heart, Sch Med, Sect Pediat Neurosurg, Dept Neurosurg, Largo AGemelli 8, I-00168 Rome, Italy Univ Sacred Heart Largo A Gemelli 8 Rome Italy I-00168 taly
Citazione:
M. Caldarelli et al., "Intra-axial dermoid/epidermoid tumors of the brainstem in children", SURG NEUROL, 56(2), 2001, pp. 97-105

Abstract

BACKGROUND Epidermoid and dermoid cysts are rare intracranial space-occupying lesions, which account for about 1% of all intracranial tumors; they are even rarer in the pediatric age group. Among the varius locations, that inside the brain stem is quite exceptional (only 12 cases reported to date in the literature). We report two additional cases occurring in children, underlining their clinical characteristics, the difficulties faced in the diagnostic work-up, and the surgical treatment adopted (which consisted of removal of the cyst contents and partial resection of the cyst membrane, because of its adherence to the surrounding nervous and vascular structures). METHODS We report two cases of intraaxial dermoid/epidermoid cysts observed within the last 5 years. Both patients complained of cervico-nuchal pain,with a remittent/intermittent character in one of them; this patient also exhibited transient 6th and 7th cranial nerve deficit. One lesion was approached through the floor of the fourth ventricle, the second one through theventrolateral aspect of the brainstem. RESULTS Subtotal tumor resection was achieved in both cases. Both patientshad a smooth postoperative course without permanent neurological deficits. In the first patient residual tumor remains stable on follow-up MRI. In the second one, early tumor regrowth necessitated a second operation, after which the residual tumor has remained stable. CONCLUSIONS Based on our experience we suggest that a cautious surgical approach ("conservative" resection) to these lesions is the best choice. In fact, attempts at radical removal carry unacceptably high morbidity and mortality rates. (C) 2001 by Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 19:50:06