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Titolo:
Spatial normalization of lesioned HMPAO-SPECT images
Autore:
Stamatakis, EA; Wilson, JTL; Wyper, DJ;
Indirizzi:
Univ Stirling, Dept Psychol, Stirling FK9 4LA, Scotland Univ Stirling Stirling Scotland FK9 4LA chol, Stirling FK9 4LA, Scotland So Gen Hosp, Inst Neurol Sci, Dept Clin Phys, Glasgow G51 4TF, Lanark, Scotland So Gen Hosp Glasgow Lanark Scotland G51 4TF gow G51 4TF, Lanark, Scotland
Titolo Testata:
NEUROIMAGE
fascicolo: 4, volume: 14, anno: 2001,
pagine: 844 - 852
SICI:
1053-8119(200110)14:4<844:SNOLHI>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRAIN SPECT; REGISTRATION; VALIDATION; PET;
Keywords:
SPECT; realignment; spatial normalization; functional imaging; basis functions; brain;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Stamatakis, EA Univ Stirling, Dept Psychol, Stirling FK9 4LA, Scotland Univ Stirling Stirling Scotland FK9 4LA FK9 4LA, Scotland
Citazione:
E.A. Stamatakis et al., "Spatial normalization of lesioned HMPAO-SPECT images", NEUROIMAGE, 14(4), 2001, pp. 844-852

Abstract

We investigated the effect of nonlinear alignment on SPECT images with lesions. Linear alignment produces reliable results but the introduction of nonlinear methods can improve matching by accounting for global brain shape. We examined the hypothesis that nonlinear alignment can introduce unwanted image distortions when lesions are present. We set out to quantify possibledistortions by constructing artificial lesions in order to obtain images with controllable characteristics. We examined the use of basis functions (in SPM96 and SPM99) and other nonlinear models (in AIR3.08) designed to achieve optimum alignment between image and template. We found that the use of models with high degrees of nonlinearity will result in unwanted deformations and that the safest way to align images with lesions is to use 12-point linear affine transformations. Masking was examined as a remedy to distortions caused by nonlinear methodologies and produced significantly improved results. (C) 2001 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/06/19 alle ore 17:57:15