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Titolo:
Normal fMRI brain activation patterns in children performing a verb generation task
Autore:
Holland, SK; Plante, E; Byars, AW; Strawsburg, RH; Schmithorst, VJ; Ball, WS;
Indirizzi:
Univ Cincinnati, Childrens Hosp Res Fdn, Cincinnati, OH 45221 USA Univ Cincinnati Cincinnati OH USA 45221 Res Fdn, Cincinnati, OH 45221 USA Univ Arizona, Tucson, AZ USA Univ Arizona Tucson AZ USAUniv Arizona, Tucson, AZ USA
Titolo Testata:
NEUROIMAGE
fascicolo: 4, volume: 14, anno: 2001,
pagine: 837 - 843
SICI:
1053-8119(200110)14:4<837:NFBAPI>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
FUNCTIONAL MRI; LANGUAGE DOMINANCE; RETROSPECTIVE ESTIMATION; WORD GENERATION; WADA TEST; DYSLEXIA; SPEECH; LATERALIZATION; ORGANIZATION; ANATOMY;
Keywords:
language; fMRI; child; pediatric; speech; MRI; brain; development;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Holland, SK Univ Cincinnati, Childrens Hosp Res Fdn, Cincinnati, OH 45221 USA Univ Cincinnati Cincinnati OH USA 45221 cinnati, OH 45221 USA
Citazione:
S.K. Holland et al., "Normal fMRI brain activation patterns in children performing a verb generation task", NEUROIMAGE, 14(4), 2001, pp. 837-843

Abstract

Although much is known concerning brain-language relations in adults, little is known about how these functions might be represented during the developmental period. We report results from 17 normal children, ages 7-18 years, who have successfully completed a word fluency paradigm during functionalmagnetic resonance imaging at 3 Tesla. Regions of activation replicate those reported for adult subjects. However, a statistically significant association between hemispheric lateralization of activation and age was found inthe children. Specifically, although most subjects at all ages showed lefthemisphere dominance for this task, the degree of lateralization increasedwith age. This study demonstrates that MRI can reveal developmental shiftsin the pattern of brain activation associated with semantic language function. (C) 2001 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/04/20 alle ore 02:35:15