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Titolo:
Evolutionary dynamics and evolutionary history in the RTE clade of non-LTRretrotransposons
Autore:
Zupunski, V; Gubensek, F; Kordis, D;
Indirizzi:
Jozef Stefan Inst, Dept Biochem & Mol Biol, Ljubljana 1001, Slovenia JozefStefan Inst Ljubljana Slovenia 1001 Biol, Ljubljana 1001, Slovenia Univ Ljubljana, Dept Chem & Biochem, Fac Chem & Chem Technol, Ljubljana, Slovenia Univ Ljubljana Ljubljana Slovenia m & Chem Technol, Ljubljana, Slovenia
Titolo Testata:
MOLECULAR BIOLOGY AND EVOLUTION
fascicolo: 10, volume: 18, anno: 2001,
pagine: 1849 - 1863
SICI:
0737-4038(200110)18:10<1849:EDAEHI>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
PHOSPHOLIPASE A(2) GENES; TRANSPOSABLE ELEMENTS; HORIZONTAL TRANSFER; GENOME EVOLUTION; CORE-SINES; DROSOPHILA; MARINER; TRANSPOSITION; VERTEBRATES; WIDESPREAD;
Keywords:
non-LTR retrotransposon; RTE clade; Bov-B LINE; horizontal transfer; evolutionary dynamics;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Kordis, D Jozef Stefan Inst, Dept Biochem & Mol Biol, Jamova 39, Ljubljana1001, Slovenia Jozef Stefan Inst Jamova 39 Ljubljana Slovenia 1001 1, Slovenia
Citazione:
V. Zupunski et al., "Evolutionary dynamics and evolutionary history in the RTE clade of non-LTRretrotransposons", MOL BIOL EV, 18(10), 2001, pp. 1849-1863

Abstract

This study examined the evolutionary dynamics of Bov-B LINEs in vertebrates and the evolution of the RTE clade of non-LTR retrotransposons. The firstfull-length reptilian Bov-B LINE clement is described; it is 3.2 kb in length, with a structural organization typical of the RTE clade of non-LTR retrotransposons. The long-term evolution of Bov-B LINEs was studied in 10 species of Squamata by analysis of a PCR-amplified 1.8-kb fragment encoding part of apurinic/apyrmidinic endonuclease, the intervening domain, and the palm/fingers subdomain of reverse transcriptase. A very high level of conservation in Squamata Bov-B long interspersed nuclear elements has been found, reaching 86% identity in the nearly 600 amino acids of ORF2. The same levelof conservation exists between the ancestral snake lineage and Ruminantia. Such a high level is exceptional when compared with the level of conservation observed in nuclear and mitochondrial proteins and in other transposable elements. The RTE clade has been found to be much more widely distributedthan previously thought, and novel representatives have been discovered inplants, brown algae, annelids, crustaceans, mollusks, echinoderms, and teleost fishes. Evolutionary relationships in the RTE clade were deduced at the amino acid level from three separate regions of ORF2. By using different independent methods, including the divergence-versus-age analysis, several examples of horizontal transfer in the RTE clade were recognized, with important implications for the existence of HT in non-LTR retrotransposons.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 21:01:25