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Titolo:
Inactivated suckling mouse brain rabies vaccine provides short-term immunity in capuchin monkeys (Cebus apella)
Autore:
Passos, EC; Germano, PML; Guimaraes, MABV; Fedullo, JDL; Correa, SHR; Consales, CA; Carrieri, ML; Goncalves, MA;
Indirizzi:
Inst Pasteur, BR-01311000 Sao Paulo, Brazil Inst Pasteur Sao Paulo Brazil BR-01311000 BCR-01311000 Sao Paulo, Brazil Secretaria Educ, BR-04372050 Sao Paulo, Brazil Secretaria Educ Sao PauloBrazil BR-04372050 BC4372050 Sao Paulo, Brazil Fundacao Parque Zool Sao Paulo, BR-04301905 Sao Paulo, Brazil Fundacao Parque Zool Sao Paulo Sao Paulo Brazil BR-04301905 BClo, Brazil Univ Sao Paulo, Fac Saude Publ, BR-01246904 Sao Paulo, Brazil Univ Sao Paulo Sao Paulo Brazil BR-01246904 BC01246904 Sao Paulo, Brazil
Titolo Testata:
JOURNAL OF ZOO AND WILDLIFE MEDICINE
fascicolo: 1, volume: 32, anno: 2001,
pagine: 55 - 57
SICI:
1042-7260(200103)32:1<55:ISMBRV>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
VIRUS;
Keywords:
rabies; vaccination; capuchin monkey; Cebus apella; suckling mouse brain vaccine; SMBV; neutralizing antibodies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Passos, EC Inst Pasteur, Av Paulista 393, BR-01311000 Sao Paulo, Brazil Inst Pasteur Av Paulista 393 Sao Paulo Brazil BR-01311000 BCil
Citazione:
E.C. Passos et al., "Inactivated suckling mouse brain rabies vaccine provides short-term immunity in capuchin monkeys (Cebus apella)", J ZOO WILD, 32(1), 2001, pp. 55-57

Abstract

Eight capuchin monkeys (Cebus apella) were vaccinated against rabies with an inactivated suckling mouse brain vaccine (SMBV). Three 1-ml doses of 2% brain tissue suspension were given by i.m. injection at 0, 30, and 60 days. Blood samples were collected at 0, 30, 60, 90, 150, 210, 240, 300, and 365days and were tested by simplified fluorescence inhibition to titer-neutralizing antibodies. All of the animals developed neutralizing antibodies with titers >0.5 IU/ml after vaccination, but the immune response persisted for only 122.3 +/- 32.6 days, The SMBV was able to induce immune response in the capuchin monkeys, but protection was short-lived.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/10/20 alle ore 16:38:17