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Titolo:
Assessment of left ventricular diastolic function with electrocardiography-gated myocardial perfusion SPECT: Comparison with multigated equilibrium radionuclide angiography
Autore:
Kumita, S; Cho, K; Nakajo, H; Toba, M; Uwamori, M; Mizumura, S; Kumazaki, T; Sano, J; Sakai, S; Munakata, K;
Indirizzi:
Nippon Med Coll, Dept Radiol, Bunkyo Ku, Tokyo 1138603, Japan Nippon Med Coll Tokyo Japan 1138603 iol, Bunkyo Ku, Tokyo 1138603, Japan Nippon Med Coll, Dept Internal Med 1, Tokyo 113, Japan Nippon Med Coll Tokyo Japan 113 l, Dept Internal Med 1, Tokyo 113, Japan
Titolo Testata:
JOURNAL OF NUCLEAR CARDIOLOGY
fascicolo: 5, volume: 8, anno: 2001,
pagine: 568 - 574
SICI:
1071-3581(200109/10)8:5<568:AOLVDF>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; HYPERTROPHIC CARDIOMYOPATHY; TECHNETIUM-99M-SESTAMIBI SPECT; EJECTION FRACTION; QUANTIFICATION; IMPROVEMENT; VERAPAMIL; EXERCISE; IMAGES; HEART;
Keywords:
left ventricular diastolic function; gated single photon emission computed; tomography; radionuclide angiography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Kumita, S Nippon Med Coll, Dept Radiol, Bunkyo Ku, 1-1-5 Sendagi, Tokyo 1138603, Japan Nippon Med Coll 1-1-5 Sendagi Tokyo Japan 1138603 138603, Japan
Citazione:
S. Kumita et al., "Assessment of left ventricular diastolic function with electrocardiography-gated myocardial perfusion SPECT: Comparison with multigated equilibrium radionuclide angiography", J NUCL CARD, 8(5), 2001, pp. 568-574

Abstract

Background. Technetium-labeled myocardial! perfusion tracers allow the simultaneous assessment of myocardial perfusion and left ventricular function by electrocardiography (ECG)-gated myocardial perfusion single photon emission computed tomography (SPECT). This study evaluates left ventricular systolic and diastolic function by ECG-gated SPECT with the use of higher framing (32 frames per cardiac cycle) data acquisition. Methods and Results. After receiving an injection of technetium 99m tetrofosmin, 48 patients with cardiac diseases were examined by ECG-gated myocardial perfusion SPECT with a 3-headed gamma camera. During gated data collection, 32 frames per cardiac cycle were acquired over 360 degrees in 60 steps, each of which consisted of 60 beats. Immediately thereafter, the 32 frames taken at each projection angle were combined into 16-frame and 8-frame data sets. Left ventricular end-diastolic volume (LVEDV, in milliliters), left ventricular end-systolic volume (LVESV, in milliliters), and left ventricular ejection fraction (LVEF, percentage) were automatically calculated from the 32-frame, 16-frame, and 8-frame gated data sets. Left ventricular time-volume curves from the 3 data sets were generated by Fourier curve fitting analysis with the use of 3 harmonies, and then peak filling rate (PFR, per second) was measured. Twenty-nine patients also underwent multigated equilibrium radionuclide angiography (ERNA) to determine the LVEF and PFR. Combining the 32-frame data into 16-frame and 8-frame data sets from the 48 patients generated a smaller LVEDV and a larger LVESV, and LVEF was significantly lower in accordance with the decreasing number of frames. Compared withERNA studies (n=29), the Bland-Altman method showed underestimated LVEFs and larger 95% limits of agreement in lower framing gated SPECT. Conclusions. Left ventricular functional parameters obtained from 32-framegated SPECT correlated closely with those determined by ERNA studies. ECG-gated SPECT with 32-frame data can provide comprehensive information with which to evaluate many types of cardiac diseases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/09/19 alle ore 23:12:00