Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Gas chromatographic-mass spectrometric method for quantitation of phenylalanine and tyrosine in serum
Autore:
Laurens, JB; Mbianda, XY; Ubbink, JB; Vermaak, WJH;
Indirizzi:
Univ Pretoria, Fac Med, Dept Clin Pathol, ZA-0001 Pretoria, South Africa Univ Pretoria Pretoria South Africa ZA-0001 -0001 Pretoria, South Africa
Titolo Testata:
JOURNAL OF CHROMATOGRAPHY B
fascicolo: 2, volume: 762, anno: 2001,
pagine: 127 - 136
SICI:
1387-2273(20011025)762:2<127:GCSMFQ>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
PHASE LIQUID-CHROMATOGRAPHY; DRIED BLOOD SPOTS; FILTER-PAPER; AMINO-ACIDS; PHENYLKETONURIA; SPECIMENS; SYSTEM; ASSAY; DEHYDROGENASE; PKU;
Keywords:
phenylalanine; tyrosine; phenylketonuria;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Laurens, JB Univ Pretoria, Fac Med, Dept Clin Pathol, POB 2034, ZA-0001 Pretoria, South Africa Univ Pretoria POB 2034 Pretoria South Africa ZA-0001 h Africa
Citazione:
J.B. Laurens et al., "Gas chromatographic-mass spectrometric method for quantitation of phenylalanine and tyrosine in serum", J CHROMAT B, 762(2), 2001, pp. 127-136

Abstract

A validated gas chromatographic-mass spectrometric method for quantitationof phenylalanine and tyrosine, in serum is described. Quantitation of phenylalanine and tyrosine with a non-labelled non-endogenous internal standard, L-2-chlorophenylalanine, compared favourably with isotope dilution mass spectrometric quantitation. The 95% reference ranges for phenylalanine, tyrosine and the phenylalanine-tyrosine molar ratio in neonate cord blood serumwere determined by isotope dilution mass spectrometry and were found to be77.1-144.7, 33.3-109.3 mu mol/l and 1.1-3.0, respectively. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 21:24:20