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Titolo:
Stress-induced changes in subendocardial tissue texture in hypertrophic cardiomyopathy: An echocardiographic videodensitometric study
Autore:
Pingitore, A; Picano, E; Paterni, M; Passera, M;
Indirizzi:
CNR, Inst Clin Physiol, I-56100 Pisa, Italy CNR Pisa Italy I-56100CNR, Inst Clin Physiol, I-56100 Pisa, Italy
Titolo Testata:
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
fascicolo: 4, volume: 17, anno: 2001,
pagine: 245 - 252
SICI:
0167-9899(200108)17:4<245:SCISTT>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
MYOCARDIAL GRAY-LEVEL; CORONARY FLOW RESERVE; INTEGRATED BACKSCATTER; DIPYRIDAMOLE-ECHOCARDIOGRAPHY; ULTRASONIC BACKSCATTER; VASODILATOR RESERVE; ISCHEMIA; IDENTIFICATION; AMPLITUDE; MARKER;
Keywords:
dipyridamole; hypertrophic cardiomyopathy; stress echocardiography; ultrasonic tissue characterization;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Pingitore, A CNR, Inst Clin Physiol, Via Morutti 1, I-56100 Pisa, Italy CNR Via Morutti 1 Pisa Italy I-56100 1, I-56100 Pisa, Italy
Citazione:
A. Pingitore et al., "Stress-induced changes in subendocardial tissue texture in hypertrophic cardiomyopathy: An echocardiographic videodensitometric study", INT J CARDI, 17(4), 2001, pp. 245-252

Abstract

Background: Myocardial ischemia changes myocardial acoustic properties, inducing increase of integrated backscatter and blunting of cyclic variation of backscatter. Stress-induced subendocardial underperfusion has been demonstrated in patients with hypertrophic cardiomyopathy (HCM). Aim: To evaluate the potential of a videodensitometric approach in assessing transmural ultrasonic tissue changes in HCM during dipyridamole infusion. Methods: Twenty-two patients (13 males, 50 +/- 12 years) with HCM underwent dipyridamole echo testing (DET). Myocardial gray levels amplitude was calculated off-line on digitized images in the left subendocardial (LV-endo), right subendocardial (RV-endo) region of the interventricular septum and posterior wall (long axis parasternal view). Results: The thickness of the interventricular septum and posterior wall was 1.9 +/- 0.3 and 1.17 +/- 2.1 cm, respectively. In the LV-endo layer, the cyclic variation was blunted during DET (rest =37 +/- 14 vs. DET 27 +/- 20%, p < 0.02). In the RV-endo layer and posterior wall, no changes occurred. In the LV-endo layer of the septum, blunting of cyclic variation was more pronounced in the 10 patients with than in the 12 without ST-segment depression during DET (21.2 +/- 14.7% vs. 43.8 +/- 15.8, p < 0.01). Conclusions: In HCM patients, DET induced blunting of cyclicvariation without the evidence of wall motion abnormalities. This reduction was more pronounced when electrocardiographic signs of ischemia were simultaneously elicited by DET.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 11:36:46