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Titolo:
EVALUATION OF THE BIOCOMPATIBILITY OF A NONCERAMIC HYDROXYAPATITE
Autore:
LIU CS; WANG WB; SHEN W; CHEN TY; HU LM; CHEN ZW;
Indirizzi:
E CHINA UNIV SCI & TECHNOL,INST TECH CHEM PHYS,POB 258,130 MEILONG RDSHANGHAI 200237 PEOPLES R CHINA SHANGHAI MED UNIV,ZHONGSHAN HOSP SHANGHAI 200032 PEOPLES R CHINA
Titolo Testata:
Journal of endodontics
fascicolo: 8, volume: 23, anno: 1997,
pagine: 490 - 493
SICI:
0099-2399(1997)23:8<490:EOTBOA>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
CALCIUM-PHOSPHATE; CEMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
12
Recensione:
Indirizzi per estratti:
Citazione:
C.S. Liu et al., "EVALUATION OF THE BIOCOMPATIBILITY OF A NONCERAMIC HYDROXYAPATITE", Journal of endodontics, 23(8), 1997, pp. 490-493

Abstract

In this study, the biocompatibility of calcium phosphate cement (CPC)was systematically investigated, which included systemic injection acute toxicity assay, cell culture cytotoxicity assay, gene mutation assay (Ames test), chromosome aberration assay (micronucleus test), DNA damage assay (unscheduled DNA synthesis test) and implant histological evaluation. The results showed that the CPC had no toxicity and all tests for mutagenicity and potential carcinogenicity of CPC extracts arenegative. CPC was implanted into the femurs of rabbits under no-load condition and the histology of specimens revealed that the implant tightly joined with the surrounding bone, only a very slight histologicalinflammatory reaction occurred. Thus, CPC is a highly biocompatible material and seems to be safe for application in humans.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 12:53:17