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Titolo:
Ligands to the melanocortin receptors
Autore:
Andersson, PM; Boman, A; Seifert, E; Skottner, A; Lundstedt, T;
Indirizzi:
Melacure Therapeut AB, SE-75643 Uppsala, Sweden Melacure Therapeut AB Uppsala Sweden SE-75643 , SE-75643 Uppsala, Sweden Uppsala Univ, Dept Organ Pharmaceut Chem, BMC, SE-75124 Uppsala, Sweden Uppsala Univ Uppsala Sweden SE-75124 Chem, BMC, SE-75124 Uppsala, Sweden
Titolo Testata:
EXPERT OPINION ON THERAPEUTIC PATENTS
fascicolo: 10, volume: 11, anno: 2001,
pagine: 1583 - 1592
SICI:
1354-3776(200110)11:10<1583:LTTMR>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
MELANOCYTE-STIMULATING HORMONE; NEUROPEPTIDE ALPHA-MSH; FOOD-INTAKE; MC4 RECEPTOR; MOLECULAR-CLONING; SELECTIVE ANTAGONIST; SEXUAL-BEHAVIOR; MESSENGER-RNA; ACTH RECEPTOR; IN-VITRO;
Keywords:
WR ligands; melanocortin receptors; organic compound; peptide; therapeutic utility;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
78
Recensione:
Indirizzi per estratti:
Indirizzo: Andersson, PM Melacure Therapeut AB, Ullerakersvagen 38, SE-75643 Uppsala,Sweden Melacure Therapeut AB Ullerakersvagen 38 Uppsala Sweden SE-75643
Citazione:
P.M. Andersson et al., "Ligands to the melanocortin receptors", EXPERT OP T, 11(10), 2001, pp. 1583-1592

Abstract

This review will give a brief overview of the pharmacology of the melanocortin receptors (MCRs) as a background. The review will not handle the patents or patent applications dealing with cloning of the different subtypes ofthe receptor, since this has been recently reviewed [ii. This review will focus on different ligands acting either as agonists or antagonists to the different subtypes of the receptor, i.e., MC1R, MC3R, MC4R, and MC5R. Just recently a number of patent applications have reached the public domain, which describe small peptides or low molecular weight organic compounds binding and acting on the MCRs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 18:55:48