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Titolo:
Helicobacter pylori eradication in functional dyspepsia: new evidence for symptomatic benefit
Autore:
Malfertheiner, P;
Indirizzi:
Otto Von Guericke Univ, Dept Gastroenterol Hepatol & Infect Dis, D-39120 Magdeburg, Germany Otto Von Guericke Univ Magdeburg Germany D-39120 9120 Magdeburg, Germany
Titolo Testata:
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
, volume: 13, anno: 2001, supplemento:, 2
pagine: S9 - S11
SICI:
0954-691X(200108)13:<S9:HPEIFD>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
NONULCER DYSPEPSIA; DOUBLE-BLIND; IMPROVE SYMPTOMS; INFECTION;
Keywords:
functional dyspepsia; Helicobacter pylori; eradication; symptom improvement;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Malfertheiner, P Otto Von Guericke Univ, Dept Gastroenterol Hepatol & Infect Dis, LeipzigerStr 44,Haus 39, D-39120 Magdeburg, Germany Otto Von Guericke Univ Leipziger Str 44,Haus 39 Magdeburg Germany D-39120
Citazione:
P. Malfertheiner, "Helicobacter pylori eradication in functional dyspepsia: new evidence for symptomatic benefit", EUR J GASTR, 13, 2001, pp. S9-S11

Abstract

Several large studies investigating the benefit of eradicating Helicobacter pylori in patients with functional dyspepsia have reported varying results, and therefore questions about the clinical management of H. pylori infection remain. The ELAN study, a recent large multicentre, randomized study, compared eradication of H. pylori (with lansoprazole and antibiotics) with acid-suppressant treatment alone (lansoprazole) in H. pylori-associated functional dyspepsia. Investigators found that eradication led to improvement of dyspeptic symptoms. Although the symptomatic benefit was limited to a small subset of patients (approximately 9%) with H. pylori-positive functional dyspepsia, cure of chronic gastritis can be offered to the majority of patients (approximately 80%) and thus, in addition to the elimination of symptoms in some, the key risk factor for gastroduodenal pathology is eliminated. This study provides support for the recommendations of Maastricht 2, which found that H. pylori eradication is an appropriate therapeutic option for functional dyspepsia. Eur J Gastroenterol Hepatol 13 (suppl 2):S9-S11 (C)2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 13:23:51