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Titolo:
Spatial and temporal analysis of left ventricular filling flow propagationin hypertensive patients before and after regression of myocardial hypertrophy with alacepril therapy
Autore:
Nobuoka, S; Nagashima, J; Hatano, S; Fujimaki, R; Saito, K; Tokuoka, S; Ando, H; Miyake, F;
Indirizzi:
St Marianna Univ, Sch Med, Dept Internal Med, Div Cardiol,Miyamae Ku, Kawasaki, Kanagawa 2168511, Japan St Marianna Univ Kawasaki Kanagawa Japan 2168511 Kanagawa 2168511, Japan
Titolo Testata:
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
fascicolo: 6, volume: 18, anno: 2001,
pagine: 479 - 483
SICI:
0742-2822(200108)18:6<479:SATAOL>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
MODE DOPPLER-ECHOCARDIOGRAPHY; DIASTOLIC FUNCTION; MASS; IMPROVEMENT; REVERSAL;
Keywords:
flow propagation velocity; diastolic function; hypertensive left ventricular hypertrophy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Nobuoka, S St Marianna Univ, Sch Med, Dept Internal Med, Div Cardiol,Miyamae Ku, 2-16-1,Sugao, Kawasaki, Kanagawa 2168511, Japan St Marianna Univ 2-16-1,Sugao Kawasaki Kanagawa Japan 2168511 n
Citazione:
S. Nobuoka et al., "Spatial and temporal analysis of left ventricular filling flow propagationin hypertensive patients before and after regression of myocardial hypertrophy with alacepril therapy", ECHOCARDIOG, 18(6), 2001, pp. 479-483

Abstract

The purpose of this study was to assess the clinical significance of spatial and temporal analysis of left ventricular (LV) filling-flow propagation using color M-mode Doppler echocardiography before and after regression of LV hypertrophy in patients with hypertension. Seven patients with hypertensive LV hypertrophy were studied. Echocardiographic and Doppler examinationswere performed both before and after 6 months administration of alacepril. LV mass index (LVMI), LV flow propagation velocity (FPV), and the maximal early transmitral flow velocity (E) were measured. LVMI, FPV, and FPV/E ratio were compared to before and after administration of alacepril. In addition, the correlation between LVMI and FPV/E ratio was evaluated. Results showed that LVMI was significantly decreased (P < 0.05) and the FPV/E ratio was significantly increased (P < 0.05) after treatment with alacepril. There was no significant change in FPV. In addition, there was a significant negative correlation between LVMI and the FPV/E ratio (r = -0.662, P < 0.001). The present study indicates that the FPV/E ratio could be a useful noninvasive parameter to assess the diastolic dysfunction associated with LV hypertrophy in patients with hypertension.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 06:14:17