Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Apoptotic cell removal
Autore:
Henson, PM; Bratton, DL; Fadok, VA;
Indirizzi:
Natl Jewish Med & Res Ctr, Cell Biol Program, Denver, CO 80206 USA Natl Jewish Med & Res Ctr Denver CO USA 80206 ogram, Denver, CO 80206 USA Natl Jewish Med & Res Ctr, Dept Pediat, Denver, CO 80206 USA Natl Jewish Med & Res Ctr Denver CO USA 80206 ediat, Denver, CO 80206 USA
Titolo Testata:
CURRENT BIOLOGY
fascicolo: 19, volume: 11, anno: 2001,
pagine: R795 - R805
SICI:
0960-9822(20011002)11:19<R795:ACR>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEMBRANE PHOSPHOLIPID SCRAMBLASE; BINDING CASSETTE TRANSPORTER-1; MONOCYTE-DERIVED MACROPHAGES; B SCAVENGER RECEPTOR; CAENORHABDITIS-ELEGANS; SALMONELLA-TYPHIMURIUM; VITRONECTIN RECEPTOR; DENDRITIC CELLS; PLASMA-MEMBRANE; C-ELEGANS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
118
Recensione:
Indirizzi per estratti:
Indirizzo: Henson, PM Natl Jewish Med & Res Ctr, Cell Biol Program, 1400 Jackson St, Denver, CO 80206 USA Natl Jewish Med & Res Ctr 1400 Jackson St Denver CO USA 80206 A
Citazione:
P.M. Henson et al., "Apoptotic cell removal", CURR BIOL, 11(19), 2001, pp. R795-R805

Abstract

Ingestion by professional or amateur phagocytes is the fate of most cells that undergo apoptosis. Studies in both Caenorhabditis elegans and mammals are now converging to reveal some of the key mechanisms and consequences ofthis removal process. At least seven corpse removal genes in nematodes have mammalian equivalents, and represent elements of signaling pathways involved in uptake. In mammals, a wide variety of apoptotic cell recognition receptors has been implicated and appears to be divided into two categories, involved in tethering the apoptotic cell or triggering an uptake mechanism related to macropinocytosis. Apoptotic cell removal is normally efficient and non-inflammatory. By contrast, the process may become subverted by parasites to yield a more favorable growth environment, or in other cases lead tofibrosis. Removal may also clinch the apoptotic process itself in cells not yet completely committed to death. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 13:01:25