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Titolo:
Chromobacterium violaceum: A review of pharmacological and industiral perspectives
Autore:
Duran, N; Menck, CFM;
Indirizzi:
Univ Estadual Campinas, Inst Quim, Biol Chem Lab, BR-13083970 Campinas, SP, Brazil Univ Estadual Campinas Campinas SP Brazil BR-13083970 BCpinas, SP, Brazil Univ Sao Paulo, Inst Ciencias Biomed, Dept Microbiol, BR-05508 Sao Paulo, Brazil Univ Sao Paulo Sao Paulo Brazil BR-05508 iol, BR-05508 Sao Paulo, Brazil Univ Mogi das Cruzes, Nucleo Ciencias Ambientais, Mogi das Cruzes, SP, Brazil Univ Mogi das Cruzes Mogi das Cruzes SP Brazil gi das Cruzes, SP, Brazil
Titolo Testata:
CRITICAL REVIEWS IN MICROBIOLOGY
fascicolo: 3, volume: 27, anno: 2001,
pagine: 201 - 222
SICI:
1040-841X(2001)27:3<201:CVAROP>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
HISTONE DEACETYLASE INHIBITOR; EXTRACELLULAR CYTOSINE DEAMINASE; CHRONIC GRANULOMATOUS-DISEASE; CHRONIC LYMPHOCYTIC-LEUKEMIA; 1ST CASE-REPORT; PHENYLALANINE-HYDROXYLASE; TRYPTOPHAN-METABOLISM; ACUTE PLEUROPNEUMONIA; BACTERIAL CHEMISTRY; ACID-SEQUENCE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
189
Recensione:
Indirizzi per estratti:
Indirizzo: Duran, N Univ Estadual Campinas, Inst Quim, Biol Chem Lab, CP 6154, BR-13083970 Campinas, SP, Brazil Univ Estadual Campinas CP 6154 Campinas SP Brazil BR-13083970 BCl
Citazione:
N. Duran e C.F.M. Menck, "Chromobacterium violaceum: A review of pharmacological and industiral perspectives", CR R MICROB, 27(3), 2001, pp. 201-222

Abstract

Violet-pigmented bacteria, which have been described since the end of the 19th century, are occasionally the causative agent of septicemia and sometimes cause fatal infection in human and animals. Bacteria, producing violet colonies due to the production of a nondiffusible pigment violacein, were classified as a redefined genus Chromobacterium. Chromobacterium violaceum is Gram-negative, and saprophyte from soil and water is normally considered nonpathogenic to human, but is an opportunistic pathogen of extreme virulence for human and animals. The biosynthesis and biological activities of violacein and the diverse effects of this pigment have been studied. Besides violacein, C. violaceum produces other antibiotics, such as aerocyanidin andaerocavin, which exhibit in vitro activity against both Gram-negative and Gram-positive bacteria. 3,6-Dihydroxyindoxazene and Y-TO678h exhibit a selective activity against Gram-negative bacteria. Arphamenine A and B, and FR901228, that enhanced immunoresponse, and potentiators of beta -lactam antibiotics and chelators such as ferrioxamine exhibit important clinical potential applications. Lipopolysaccharides and polyhydroxyesters together with several enzymes appear as important metabolites with biotechnological applications. Many of these metabolites were already studied at the genome level.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 19:21:32