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Titolo:
Plasma colloid osmotic pressure in healthy infants
Autore:
Sussmane, JB; de Soto, M; Torbati, D;
Indirizzi:
Miami Childrens Hosp, Div Crit Care Med, Miami, FL 33155 USA Miami Childrens Hosp Miami FL USA 33155 rit Care Med, Miami, FL 33155 USA
Titolo Testata:
CRITICAL CARE
fascicolo: 5, volume: 5, anno: 2001,
pagine: 261 - 264
SICI:
1466-609X(200110)5:5<261:PCOPIH>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
FLUID RESUSCITATION; CRITICALLY ILL; ALBUMIN; DEBATE;
Keywords:
colloid osmotic pressure; colloid therapy; fluid balance; infant patients; neonate patients;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Torbati, D Miami Childrens Hosp, Div Crit Care Med, Miami, FL 33155 USA Miami Childrens Hosp Miami FL USA 33155 d, Miami, FL 33155 USA
Citazione:
J.B. Sussmane et al., "Plasma colloid osmotic pressure in healthy infants", CRIT CARE, 5(5), 2001, pp. 261-264

Abstract

Background The plasma colloid osmotic pressure (COP) plays a major role intranscapillary fluid balance. There is no information on plasma COP of healthy infants beyond the first post-natal week, The normal COP in healthy adult subjects (25 mmHg) is currently also applied as a reference value for healthy infants. This study was designed to test whether plasma COP values in healthy infants are the same as those in normal adults. Methods Plasma COP was measured in 37 male and female healthy infants from1 to 11 months old. For this purpose, 1 ml blood was collected during the patient's regularly scheduled visit if the patient required any type of blood test for routine laboratory analyses. Results Plasma COP levels correlated slightly with increasing age from 1 to 9 months old (linear regression analysis; r(2)=0.1, P<0.049). We found nocorrelation between plasma COP and body weight at the same age (r(2)=0.05,P=0.155). The mean and standard deviation of COP in all infants was 25.1<plus/minus>2.6 mmHg, which is almost identical to an average COP of 25 mmHg in healthy adult subjects. Arbitrary division of the infants into three different age groups (1-3 months [n=11], 5-8 months [n=13] and 9-11 months [n=13]) showed an average increase of approximately 2 mmHg in COP of 9-month-old to 11-month-old infants, compared with 1-month-old to 3-month-old infants (one-way analysis of variance; P=0.26). There was no gender difference inthe COP level (unpaired t-test), with an average of 25.1 +/-2.4 mmHg in 19male infants compared with 25.2 +/-2.9 in 18 female infants. The 95% confidence interval for COP in both male and female infants (n=37) was between 24.3 to 26.0 mmHg, ranging from 19.5 to 30.3 mmHg, with a median value of 25.2 mmHg. Conclusions The data accept the null hypothesis that the COP range in infants younger than I year old is similar to those observed in adult subjects. Our observations, compared with previously reported neonatal COP values, suggest that there is a sharp increase in COP within the first months after birth.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 21:02:30