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Titolo:
Major and c-series gangliosides in lenticular tissues: mammals to molluscs
Autore:
Saito, M; Sugiyama, K;
Indirizzi:
Univ Shizouka, Sch Pharmaceut Sci, Dept Clin Pharmacol & Therapeut, Shizuoka 4228526, Japan Univ Shizouka Shizuoka Japan 4228526 Therapeut, Shizuoka 4228526, Japan
Titolo Testata:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
fascicolo: 3, volume: 130, anno: 2001,
pagine: 313 - 321
SICI:
1096-4959(200110)130:3<313:MACGIL>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
LENS EPITHELIAL-CELLS; ACIDIC GLYCOSPHINGOLIPIDS; MONOCLONAL-ANTIBODY; CATARACTOUS LENSES; RHESUS-MONKEY; BRAIN; EXPRESSION; LEWIS(X); DIFFERENTIATION; CHROMATOGRAPHY;
Keywords:
gangliosides; C-series gangliosides; A2B5; eye lenses; phylogeny; fish; mollusc; squid; octopus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
49
Recensione:
Indirizzi per estratti:
Indirizzo: Saito, M Univ Shizouka, Sch Pharmaceut Sci, Dept Clin Pharmacol & Therapeut, 52-1 Yada, Shizuoka 4228526, Japan Univ Shizouka 52-1 Yada Shizuoka Japan 4228526 ka 4228526, Japan
Citazione:
M. Saito e K. Sugiyama, "Major and c-series gangliosides in lenticular tissues: mammals to molluscs", COMP BIOC B, 130(3), 2001, pp. 313-321

Abstract

Gangliosides of eye lenses were examined in mammals (rat, rabbits, pig, cow), bird (chicken), reptile (terrapin), amphibian (bullfrog), bony fish (red sea bream, bluefin tuna, bonito, Pacific mackerel) and molluscs (common squid, Pacific octopus), Besides the fact that GM3 was the common ganglioside species, the composition of major gangliosides in mammalian eye lenses significantly differed from each other. While gangliotetraose gangliosides were abundant in rat eye lens, they did not constitute major components in porcine and bovine tissues. The c-series ganglioside GT3 was expressed in rateye lenses but were practically absent in other mammalian tissues. The composition of major gangliosides in eye lenses of lower animals varied from species to species, whereas c-series gangliosides were consistently expressed, showing similar compositional profiles. Our results demonstrate the species-specific compositions of lenticular gangliosides. Evidence was also provided suggesting that eye lenses of common squid (Todarodes pacificus) and Pacific octopus (Octopus vulgaris) express gangliosides including gangliotetraose species and c-series gangliosides. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 15:34:04