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Titolo:
Natural course of lymphocytic infundibuloneurohypophysitis
Autore:
Amagasa, M; Yuda, F; Kojima, H; Noshita, N; Sato, S;
Indirizzi:
Yamagata City Hosp Saiseikan, Dept Neurosurg, Yamagata 9908533, Japan Yamagata City Hosp Saiseikan Yamagata Japan 9908533 agata 9908533, Japan Yamagata City Hosp Saiseikan, Dept Pathol, Yamagata 9908533, Japan Yamagata City Hosp Saiseikan Yamagata Japan 9908533 agata 9908533, Japan Tokyo Metropolitan Inst Neurosci, Dept Clin Neuropathol, Tokyo, Japan Tokyo Metropolitan Inst Neurosci Tokyo Japan Neuropathol, Tokyo, Japan
Titolo Testata:
CLINICAL NEUROPATHOLOGY
fascicolo: 5, volume: 20, anno: 2001,
pagine: 229 - 232
SICI:
0722-5091(200109/10)20:5<229:NCOLI>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIABETES-INSIPIDUS; GRANULOMATOUS HYPOPHYSITIS; HYPOPITUITARISM; VARIANT;
Keywords:
pituitary gland; granulomatous hypophysitis; lymphocytic hypophysitis; sinusitis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Amagasa, M Yamagata City Hosp Saiseikan, Dept Neurosurg, 1-3-26 Nanoka Machi, Yamagata 9908533, Japan Yamagata City Hosp Saiseikan 1-3-26 Nanoka Machi Yamagata Japan 9908533
Citazione:
M. Amagasa et al., "Natural course of lymphocytic infundibuloneurohypophysitis", CLIN NEUR, 20(5), 2001, pp. 229-232

Abstract

Natural course of lymphocytic infundibuloneurohypophysitis is poorly understood. A 49-year-old male had noticed being unnaturally thirsty since abouttwo years previously. An enlargement of the pituitary stalls and pituitarygland was thus observed by MR at that time. However, no medical care had been given. Two years later, he was admitted to our hospital due to headachein addition to panhypopituitarism. The histologic features included T celldominant lymphocytes infiltrating prominently the entire pituitary gland with a small amount of multinucleated giant cells, focal and small necrosis,cholesterin crystals and granuloma. Neither tuberculosis nor Langerhans histiocytosis were observed. In addition, the patient was found to have a unique massive well-encapusulated lesion in the sphenoid sinus, just below thepituitary fossa, consisting of serous fluid, normal columnar epithelium and submucosal fibrosis. This patient had a fairly typical clinical manifestation of lymphocytic infundibuloneurohypophysitis with invason of the posterior lobe and the stalk. The lesion became chronic and leaked to the sphenoid sinus. As a result, chronic hypophysitis with granuloma formation thus occurred. This case may show the course of this disease if not treated.

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Documento generato il 05/12/20 alle ore 00:52:49