Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Mechanisms of tension-type headache
Autore:
Jensen, R;
Indirizzi:
Univ Copenhagen, Glostrup Hosp, Dept Neurol, DK-2600 Glostrup, Denmark Univ Copenhagen Glostrup Denmark DK-2600 urol, DK-2600 Glostrup, Denmark
Titolo Testata:
CEPHALALGIA
fascicolo: 7, volume: 21, anno: 2001,
pagine: 786 - 789
SICI:
0333-1024(200109)21:7<786:MOTH>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRESSURE PAIN THRESHOLDS; NITRIC-OXIDE SYNTHASE; GENERAL-POPULATION; MUSCLE HARDNESS; PATHOPHYSIOLOGICAL MECHANISMS; MIGRAINE; STATE; EPIDEMIOLOGY; TENDERNESS; DISORDERS;
Keywords:
tension-type headache; pathophysiology; peripheral sensitization; central sensitization; NO-donor; NOS-inhibitor;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Jensen, R Univ Copenhagen, Glostrup Hosp, Dept Neurol, DK-2600 Glostrup, Denmark Univ Copenhagen Glostrup Denmark DK-2600 600 Glostrup, Denmark
Citazione:
R. Jensen, "Mechanisms of tension-type headache", CEPHALALGIA, 21(7), 2001, pp. 786-789

Abstract

Despite tension-type headache represents one of the most frequent and costly diseases in modem society only very little research on this disease has actually been carried out. In contrast to former belief tension-type headache is a separate entity that can and should be separated from migraine. No specific biochemical abnormalities have yet been identified but a reliable human model of tension-type headache has been developed by means of infusion of a NO-donor, glyceryl trinitrate. Myofascial factors and, peripheral sensitization of nociceptors play an important role in the episodic form, andcentral sensitization has been demonstrated in the chronic form. As chronic tension-type headache usually evolves from the episodic form, prevention and reversal of this central sensitization may be an important target for future pathophysiological studies and drug development.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 15:08:52