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Titolo:
Cutaneous larva migrans: clinical features and management of 44 cases presenting in the returning traveller
Autore:
Blackwell, V; Vega-Lopez, F;
Indirizzi:
Univ Coll London Hosp Trust, Middlesex Hosp, Dept Dermatol, London W1P 9PG, England Univ Coll London Hosp Trust London England W1P 9PG ndon W1P 9PG, England Univ Coll London Hosp Trust, Hosp Trop Dis, London W1P 9PG, England Univ Coll London Hosp Trust London England W1P 9PG ndon W1P 9PG, England
Titolo Testata:
BRITISH JOURNAL OF DERMATOLOGY
fascicolo: 3, volume: 145, anno: 2001,
pagine: 434 - 437
SICI:
0007-0963(200109)145:3<434:CLMCFA>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
THERAPEUTIC REGIMEN; ALBENDAZOLE;
Keywords:
cutaneous larva migrans; travellers; tropical dermatology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Vega-Lopez, F Univ Coll London Hosp Trust, Middlesex Hosp, Dept Dermatol, Arthur StanleyHouse,Tottenham St, London W1P 9PG, England Univ Coll London Hosp Trust Arthur Stanley House,Tottenham St London England W1P 9PG
Citazione:
V. Blackwell e F. Vega-Lopez, "Cutaneous larva migrans: clinical features and management of 44 cases presenting in the returning traveller", BR J DERM, 145(3), 2001, pp. 434-437

Abstract

Background Cutaneous larva migrans (CLM) is the result of a nematode infection, and shows a characteristic creeping eruption. As travel to the tropics increases, many British citizens may be returning with this infection, which is often misdiagnosed or treated incorrectly. Objectives To perform a retrospective survey of 44 cases of CLM presentingto the Hospital for Tropical Diseases in London over the last 2 years. Methods Cases were reviewed with regard to patient characteristics, sourceof infection, source of referral, clinical features and therapy. Results Most infections were acquired in Africa (32%), the Caribbean (30%)and South-east Asia (25%), but also in Central and South America. There was a history of exposure to a beach in 95% of patients and the median duration of symptoms was 8 weeks (range 1-104). Lesions mainly affected the feet (39%), buttocks (18%) and abdomen (16%), but the lower leg, arm and face were also affected. Multiple lesions were seen in seven of 44 cases (16%). Laboratory abnormalities were absent in all patients. Of 44 patients seen, four needed no treatment, 28 were cured by a single course of treatment, 11 required a second course of therapy and one patient was treated three times. Thirty-one patients received oral albendazole 400 mg daily for 3-5 days and 24 were cured (77%). Five patients received 10% thiabendazole cream topically for 10 days and four were cured (80%). Four patients received oral thiabendazole 1.5 g daily for 3 days and all required further therapy. Conclusions In view of the range of treatment regimens recorded, a randomized controlled trial comparing topical and systemic therapies is warranted.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 05:33:06