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Titolo:
In vitro performance characteristics of high-frequency oscillatory ventilators
Autore:
Pillow, JJ; Wilkinson, MH; Neil, HL; Ramsden, CA;
Indirizzi:
TVW Telethon Inst Child Hlth Res, Perth, WA, Australia TVW Telethon Inst Child Hlth Res Perth WA Australia Perth, WA, Australia Univ Western Australia, Dept Paediat, Perth, WA 6009, Australia Univ Western Australia Perth WA Australia 6009 Perth, WA 6009, Australia King Edqard & Princess Margaret Hosp, Perth, WA, Australia King Edqard & Princess Margaret Hosp Perth WA Australia h, WA, Australia Monash Univ, Inst Reprod & Dev, Ritchie Ctr Baby Hlth Res, Clayton, Vic 3168, Australia Monash Univ Clayton Vic Australia 3168 Res, Clayton, Vic 3168, Australia Monash Univ, Dept Paediat, Clayton, Vic 3168, Australia Monash Univ Clayton Vic Australia 3168 diat, Clayton, Vic 3168, Australia
Titolo Testata:
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
fascicolo: 6, volume: 164, anno: 2001,
pagine: 1019 - 1024
SICI:
1073-449X(20010915)164:6<1019:IVPCOH>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESPIRATORY-DISTRESS SYNDROME; CONVENTIONAL MECHANICAL VENTILATION; ALVEOLAR PRESSURE; PRETERM INFANTS; TIDAL VOLUME; GAS-EXCHANGE; TRIAL; ELIMINATION; IMPEDANCE; PULMONARY;
Keywords:
compliance; high-frequency ventilation; newborn; respiratory distress syndrome; ventilator properties;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Pillow, JJ Inst Child Hlth, Portex Unit, 30 Guilford St, London WC1N 1EH, England Inst Child Hlth 30 Guilford St London England WC1N 1EH England
Citazione:
J.J. Pillow et al., "In vitro performance characteristics of high-frequency oscillatory ventilators", AM J R CRIT, 164(6), 2001, pp. 1019-1024

Abstract

This study aimed to examine the performance characteristics of four high-frequency oscillatory-type ventilators, using an in vitro model of the intubated neonatal respiratory system. Each ventilator was examined across its operative range of settings and at varying model lung compliance (C) and resistance. The oscillatory pressure waveform was measured at the airway opening (Pao). Tidal volume (VT) and flow were determined from pressure changes within the model lung (Delta PA). The spectral content of the Pao waveform differed between ventilators. The maximum ventilator VT ranged from 3.7 to 11.1 ml at 15 Hz and a mean airway pressure (Paw) of 12 cm H2O to oscillatea model lung (C = 0.4 ml/cm H2O) through a 3.0-mm internal diameter (i.d.)endotracheal tube (ETT). A small drop in C was associated with a decrease in VT and marked increase in Delta PA from 0.1 to 0.8 ml/cm H2O. The influence of C on VT and Delta PA and the pressure cost of ventilation (Delta PA/f.VT2) was dependent on the oscillatory frequency, ETT inner diameter, and the specific ventilator used. Substantive differences exist between oscillatory ventilators that need to be considered in their clinical application. The rapid establishment of optimal lung volume and oscillatory frequency isimportant in minimizing barotrauma during high-frequency oscillatory ventilation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 12:12:39