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Titolo:
Exposure-response relationship between paternal smoking and children's pulmonary function
Autore:
Venners, SA; Wang, XB; Chen, CZ; Wang, BY; Ni, JT; Jin, YT; Yang, JH; Fang, Z; Weiss, ST; Xu, XP;
Indirizzi:
Harvard Univ, Sch Publ Hlth, Program Populat Genet, Dept Environm Hlth, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 Dept Environm Hlth, Boston, MA 02115 USA Tulane Univ, Ctr Bioenvironm Res, New Orleans, LA 70118 USA Tulane Univ New Orleans LA USA 70118 ironm Res, New Orleans, LA 70118 USA Xavier Univ, Ctr Bioenvironm Res, New Orleans, LA 70125 USA Xavier Univ New Orleans LA USA 70125 ironm Res, New Orleans, LA 70125 USA Tulane Univ, US China Inst, New Orleans, LA 70118 USA Tulane Univ New Orleans LA USA 70118 hina Inst, New Orleans, LA 70118 USA Boston Univ, Sch Med, Dept Pediat, Boston, MA 02118 USA Boston Univ Boston MA USA 02118 ch Med, Dept Pediat, Boston, MA 02118 USA Boston Med Ctr, Boston, MA USA Boston Med Ctr Boston MA USABoston Med Ctr, Boston, MA USA Anhui Meizhong Inst Biomed & Environm Hlth, Anqing, Peoples R China Anhui Meizhong Inst Biomed & Environm Hlth Anqing Peoples R China China Anhui Med Univ, Inst Biomed, Anhui, Peoples R China Anhui Med Univ AnhuiPeoples R China nst Biomed, Anhui, Peoples R China Harvard Univ, Brigham & Womens Hosp, Sch Med, Channing Lab, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 Med, Channing Lab, Boston, MA 02115 USA
Titolo Testata:
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
fascicolo: 6, volume: 164, anno: 2001,
pagine: 973 - 976
SICI:
1073-449X(20010915)164:6<973:ERBPSA>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRIMARY-SCHOOL CHILDREN; RURAL CHINESE COMMUNITY; PASSIVE SMOKING; LUNG-FUNCTION; RESPIRATORY HEALTH; MATERNAL SMOKING; FAMILIAL AGGREGATION; VENTILATORY FUNCTION; PARENTAL SMOKING; RISK-FACTORS;
Keywords:
paternal smoking; environmental tobacco smoke; pulmonary function; children; China;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Xu, XP Harvard Univ, Sch Publ Hlth, Program Populat Genet, Dept Environm Hlth, 665 Huntington Ave,FXB-101, Boston, MA 02115 USA Harvard Univ 665 Huntington Ave,FXB-101 Boston MA USA 02115 115 USA
Citazione:
S.A. Venners et al., "Exposure-response relationship between paternal smoking and children's pulmonary function", AM J R CRIT, 164(6), 2001, pp. 973-976

Abstract

We conducted a cross-sectional study to investigate paternal smoking and children's pulmonary function in rural communities of Anqing, China. Our analysis included 1,718 children 8 to 15 yr of age whose mothers were never-smokers. Multiple linear regression models were used to estimate the effect of paternal smoking on children's pulmonary function, with adjustment for children's age, sex, weight, height, square of height, asthma, and father's education. When compared with children of never-smoking fathers, children ofsmoking fathers had small, but detectable deficits in FEV1 (-36 ml, SE = 20) and FVC (-37 ml, SE = 22). When children of smoking fathers were subdivided into two subgroups, father smoked <30 cigarettes/day and <greater than or equal to>30 cigarettes/day, we found that children whose fathers smoked greater than or equal to 30 cigarettes/day had the largest deficits in bothFEV1 (-79 ml, SE = 30) and FVC (-71 ml, SE = 34). This monotonic exposure-response relationship remained in all strata when we further stratified ouranalysis by children's sex and asthma status. Our data also suggested thatthe relationship was greatest among nonasthmatic girls, although neither sex nor asthma interaction terms were statistically significant. We concludethat there Is a monotonic exposure-response relationship between paternal smoking and decline of pulmonary function in children in this rural Chinesepopulation.

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Documento generato il 26/01/20 alle ore 09:45:30