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Titolo:
Echocardiographic features of the right heart in sleep-disordered breathing - The Framingham Heart Study
Autore:
Guidry, UC; Mendes, LA; Evans, JC; Levy, D; OConnor, GT; Larson, MG; Gottlieb, DJ; Benjamin, EJ;
Indirizzi:
Boston Univ, Sch Med, Ctr Pulm, Boston, MA 02118 USA Boston Univ Boston MA USA 02118 , Sch Med, Ctr Pulm, Boston, MA 02118 USA NHLBI, Framingham Heart Study, Framingham, MA USA NHLBI Framingham MA USA HLBI, Framingham Heart Study, Framingham, MA USA NHLBI, Bethesda, MD 20892 USA NHLBI Bethesda MD USA 20892NHLBI, Bethesda, MD 20892 USA Boston Univ, Sch Med, Dept Cardiol, Sect Prevent Med, Boston, MA 02118 USABoston Univ Boston MA USA 02118 l, Sect Prevent Med, Boston, MA 02118 USA Harvard Univ, Beth Israel Hosp, Sch Med, Div Cardiol, Boston, MA 02115 USAHarvard Univ Boston MA USA 02115 h Med, Div Cardiol, Boston, MA 02115 USA Harvard Univ, Beth Israel Hosp, Sch Med, Div Clin Epidemiol, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 Div Clin Epidemiol, Boston, MA 02115 USA
Titolo Testata:
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
fascicolo: 6, volume: 164, anno: 2001,
pagine: 933 - 938
SICI:
1073-449X(20010915)164:6<933:EFOTRH>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
TWO-DIMENSIONAL ECHOCARDIOGRAPHY; RIGHT-VENTRICULAR DYSFUNCTION; OBSTRUCTIVE LUNG-DISEASE; APNEA SYNDROME; PULMONARY-HYPERTENSION; INDEPENDENT PREDICTOR; CARDIAC-FUNCTION; HYPERTROPHY; OBESITY; ASSOCIATION;
Keywords:
cohort study; echocardiography; epidemiology; obesity; right ventricle; sleep-disordered breathing;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: O'Connor, GT Boston Univ, Sch Med, Ctr Pulm, Room R304,715 Albany St, Boston, MA 02118 USA Boston Univ Room R304,715 Albany St Boston MA USA 02118 8 USA
Citazione:
U.C. Guidry et al., "Echocardiographic features of the right heart in sleep-disordered breathing - The Framingham Heart Study", AM J R CRIT, 164(6), 2001, pp. 933-938

Abstract

The effect of sleep-disordered breathing (SDB) on right heart structure and function is controversial. Studies of patients referred for evaluation ofpossible sleep apnea have yielded conflicting results, and the impact of SDB on the right heart has not been investigated In the general population. We examined the echocardiographic features of subjects with SDB at the Framingham Heart Study site of the Sleep Heart Health Study. Of 1,001 polysomnography subjects, 90 with SDB defined as a respiratory disturbance index (RDI) score >90th percentile (mean RDI = 42) were compared with 90 low-RDI subjects (mean RDI = 5) matched for age, sex, and body mass index. Right heartmeasurements, made without knowledge of clinical status, were compared between groups. The majority of the subjects were male (74%). After multivariable adjustment, right ventricle (RV) wall thickness was significantly greater (p = 0.005) in subjects with SDB (0.78 +/- 0.02 cm) than in the low-RDI subjects (0.68 +/- 0.02 cm). Right atria] dimensions, RV dimensions, and RVsystolic function were not found to be significantly different between subjects with SDB and the low-RD[ subjects. We conclude that in this community-based study of SDB and right heart echocardiographic features, RV wall thickness was increased in subjects with SDB. Whether the RV hypertrophy observed in persons with SDB Is associated with increased morbidity and mortality remains unknown.

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Documento generato il 14/07/20 alle ore 06:26:56