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Titolo:
Clinical validation of true frameless stereotactic biopsy: Analysis of thefirst 125 consecutive cases
Autore:
Paleologos, TS; Dorward, NL; Wadley, JP; Thomas, DGT;
Indirizzi:
Royal Free Hosp, Dept Neurosurg, London NW3 2QG, England Royal Free Hosp London England NW3 2QG eurosurg, London NW3 2QG, England Univ London, Natl Hosp Neurol & Neurosurg, Dept Neurosurg, London, EnglandUniv London London England & Neurosurg, Dept Neurosurg, London, England
Titolo Testata:
NEUROSURGERY
fascicolo: 4, volume: 49, anno: 2001,
pagine: 830 - 835
SICI:
0148-396X(200110)49:4<830:CVOTFS>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
ISG VIEWING WAND; FIDUCIAL MARKERS; BRAIN BIOPSY; EXPERIENCE; NEURONAVIGATION; NEUROSURGERY; ACCURACY; SURGERY; IMPACT;
Keywords:
frameless stereotaxy; interactive image-guided surgery; neuronavigation; stereotactic brain biopsy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Dorward, NL Royal Free Hosp, Dept Neurosurg, Pond St, London NW3 2QG, England Royal Free Hosp Pond St London England NW3 2QG 3 2QG, England
Citazione:
T.S. Paleologos et al., "Clinical validation of true frameless stereotactic biopsy: Analysis of thefirst 125 consecutive cases", NEUROSURGER, 49(4), 2001, pp. 830-835

Abstract

OBJECTIVE: A lockable guide device, adjustable for positioning, was used to obtain samples for tissue analysis during brain biopsy procedures performed using an interactive image guidance system. Clinical validation of this technique, which was developed for true frameless stereotactic biopsies, and analyses of the histological yield, complication rate, and patient demographic characteristics for a large series of frameless stereotactic biopsieswere the purposes of this study. METHODS: Demographic, radiological, surgical, and clinical data were prospectively collected for a series of 125 frameless stereotactic biopsies performed using the technique described in detail previously. RESULTS: Eighty-six procedures were magnetic resonance imaging-directed and 39 were computed tomography-directed. The mean diameter of the biopsied lesions was 36 mm, and the mean distance from the skin was 35.8 mm. Sixteen percent of the patients harbored multiple lesions, and 5.6% of the biopsiedlesions were infratentorial. The mean operative time (including the entireanesthetic time) was 1.5 hours. The smear examination findings were corroborated by conclusive histological results in 96% of the cases, and definitive positive diagnoses were obtained in 122 cases (97.6%). Ten patients experienced surgical complications, but the sustained morbidity rate was 2.4% (including the death of a patient who was in critical clinical condition preoperatively and who died 2 mo later as a result of a chest infection; mortality rate, 0.8%). CONCLUSION: This true frameless stereotactic biopsy technique was associated with low morbidity and mortality rates and an excellent diagnostic yield, with overall results at least as good as those observed for frame-based stereotaxy. The excellent accuracy results demonstrated previously and statistically significant reductions in operative time, as well as improved image presentation, target selection, and simplicity, support the use of this frameless stereotactic technique in preference to frame-based biopsy techniques.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 23:40:46