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Titolo:
Leukemia inhibitory factor induces nociceptin mRNA in cultured rat cortical neurons
Autore:
Minami, M; Yamakuni, H; Ohtani, Y; Okada, M; Nakamura, J; Satoh, M;
Indirizzi:
Kyoto Univ, Fac Pharmaceut Sci, Dept Mol Pharmacol, Kyoto 6068501, Japan Kyoto Univ Kyoto Japan 6068501 Dept Mol Pharmacol, Kyoto 6068501, Japan
Titolo Testata:
NEUROSCIENCE LETTERS
fascicolo: 1, volume: 311, anno: 2001,
pagine: 17 - 20
SICI:
0304-3940(20010921)311:1<17:LIFINM>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIFFERENTIATION FACTOR; MESSENGER-RNA; KAINIC ACID; ORPHANIN FQ; BRAIN; LOCALIZATION; RECEPTOR; ASTROCYTES; CYTOKINES; CELLS;
Keywords:
leukemia inhibitory factor; gp130; cytokine; nociceptin; opioid; rat; cerebral cortex;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Satoh, M Kyoto Univ, Fac Pharmaceut Sci, Dept Mol Pharmacol, Kyoto 6068501, Japan Kyoto Univ Kyoto Japan 6068501 Pharmacol, Kyoto 6068501, Japan
Citazione:
M. Minami et al., "Leukemia inhibitory factor induces nociceptin mRNA in cultured rat cortical neurons", NEUROSCI L, 311(1), 2001, pp. 17-20

Abstract

The effects of leukemia inhibitory factor (LIF) on the expression of neurotransmitter synthetase and neuropeptide mRNAs in cultured rat cortical neurons were examined by reverse transcription-polymerase chain reaction. Nociceptin mRNA expression was increased by treatment with 20 or 80 ng/ml LIF for 24 h, but choline acetyl transferase, glutamic acid decarboxylase, enkephalin, dynorphin, substance P, somatostatin and galanin mRNA expression werenot altered by LIF. These observations indicated a specific effect of LIF on nociceptin gene regulation in cultured cortical neurons. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 08:51:50