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Titolo:
Beta versus gamma dosimetry close to Ir-192 brachytherapy sources
Autore:
Baltas, D; Karaiskos, P; Papagiannis, P; Sakelliou, L; Loeffler, E; Zamboglou, N;
Indirizzi:
Klinikum Offenbach, Dept Med Phys & Engn, Strahlenkin, D-63069 Offenbach, Germany Klinikum Offenbach Offenbach Germany D-63069 D-63069 Offenbach, Germany Natl Tech Univ Athens, Inst Commun & Comp Syst, GR-15773 Athens, Greece Natl Tech Univ Athens Athens Greece GR-15773 st, GR-15773 Athens, Greece Univ Athens, Dept Phys, Nucl & Particle Phys Sect, GR-15771 Athens, GreeceUniv Athens Athens Greece GR-15771 le Phys Sect, GR-15771 Athens, Greece Nucletron BV, NL-3905 TH Veenendaal, Netherlands Nucletron BV VeenendaalNetherlands NL-3905 TH H Veenendaal, Netherlands
Titolo Testata:
MEDICAL PHYSICS
fascicolo: 9, volume: 28, anno: 2001,
pagine: 1875 - 1882
SICI:
0094-2405(200109)28:9<1875:BVGDCT>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
MONTE-CARLO CALCULATION; DOSE-RATE DISTRIBUTIONS; INTRAVASCULAR BRACHYTHERAPY; STENT IMPLANTATION; AIDED DOSIMETRY; CROSS-SECTIONS; RADIATION; POINT; RADIOTHERAPY; ATTENUATION;
Keywords:
beta particles; dosimetry; endobronchial brachytherapy; intravascular brachytherapy; Ir-192; Monte Carlo simulation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Baltas, D Klinikum Offenbach, Dept Med Phys & Engn, Strahlenkin, D-63069 Offenbach, Germany Klinikum Offenbach Offenbach Germany D-63069 ffenbach, Germany
Citazione:
D. Baltas et al., "Beta versus gamma dosimetry close to Ir-192 brachytherapy sources", MED PHYS, 28(9), 2001, pp. 1875-1882

Abstract

The relative importance of the dose rate component owing to the beta spectrum emitted by Ir-192 brachytherapy sources at the short radial distances of interest in intravascular and endobronchial applications is investigated. Separate dosimetric calculations, using Monte Carlo simulations, were performed for the gamma and beta dose rate components of an Ir-192 ideal point source as weld as real Ir-192 source designs used in clinical practice including wire and seed sources and both Nucletron and Varian, old and new, high dose rate (HDR) source designs. A significant dose rate enhancement due to the beta spectrum emitted by Ir-192, greater than 50% for radial distances r < 2 mm, was observed for an ideal point source. For real source designs, however, the magnitude of this enhancement was found to depend strongly on the sources' geometric as well as compositional details of the active core and encapsulation. A detectable effect was found for the majority of the investigated sources at radial distances less than I nim, but overall findings suggest that the contribution of beta particles is not significant in Ir-192 clinical intravascular applications that are currently carried out. However, since treatment of vessels with smaller diameters, in the future, may lead to the development of Ir-192 sources and catheters of reduced diameters, the potential effect of the beta spectrum in terms of dose enhancement to tissues in close proximity to Ir-192 sources should not be ignored. (C) 2001 American Association of Physicists in Medicine.

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Documento generato il 27/09/20 alle ore 06:56:29