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Titolo:
Use of the Medication Event Monitoring System to estimate medication compliance in patients with schizophrenia
Autore:
Diaz, E; Levine, HB; Sullivan, MC; Sernyak, MJ; Hawkins, KA; Cramer, JA; Woods, SW;
Indirizzi:
Yale Univ, Connecticut Mental Hlth Ctr, Off 273A, Dept Psychiat, New Haven, CT 06519 USA Yale Univ New Haven CT USA 06519 , Dept Psychiat, New Haven, CT 06519 USA Yale Univ, Treatment Res Program, New Haven, CT 06519 USA Yale Univ New Haven CT USA 06519 ent Res Program, New Haven, CT 06519 USA
Titolo Testata:
JOURNAL OF PSYCHIATRY & NEUROSCIENCE
fascicolo: 4, volume: 26, anno: 2001,
pagine: 325 - 329
SICI:
1180-4882(200109)26:4<325:UOTMEM>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Keywords:
antipsychotic agents; drug therapy; patient compliance; psychotic disorders; schizophrenia; self administration;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: Diaz, E Yale Univ, Connecticut Mental Hlth Ctr, Off 273A, Dept Psychiat, 34 Pk St,New Haven, CT 06519 USA Yale Univ 34 Pk St New Haven CT USA 06519 ,New Haven, CT 06519 USA
Citazione:
E. Diaz et al., "Use of the Medication Event Monitoring System to estimate medication compliance in patients with schizophrenia", J PSYCH NEU, 26(4), 2001, pp. 325-329

Abstract

Objective: To determine the feasibility of using the Medication Event Monitoring System (MEMS) to estimate medication compliance in patients with schizophrenia or schizoaffective disorder. Subjects and setting: Fourteen of 35 consecutive patients admitted to a psychiatric inpatient hospital with schizophrenia or schizoaffective disorder who met eligibility requirements and gave informed consent. Intervention: After random assignment to either risperidone or typical antipsychotic treatment, medication upon discharge from hospital was dispensed in a bottle with a MEMS cap which recorded the number of bottle openings and the date and time of each opening. The first 6 patients were asked to return monthly for data downloading. The next 8 were asked to return weekly during the first month and every 2 weeks thereafter;they were also paid $5 for returning each bottle. Outcome measures: MEMS data collected over a 6-month period and hospital readmission data. Results:Patient medication compliance data were collected from 10 (71%) of 14 patients during the first month, from 7 (58%) of 12 (2 patients dropped out) during the second and from 5 (45%) of 11 (a third patient dropped out) duringmonths 3-6. Mean compliance rates were 63% for the first month and ranged from 56% to 45% over the next 5. First-month compliance rates were significantly lower for those who were subsequently readmitted to hospital (n = 7) than for those who were not (p < 0.01). Conclusions: Electronic monitoring devices can be used to estimate compliance with medication regimens in patients with severe schizophrenic disorders, but there are methodological improvements that can be made to increase data recovery and compliance, and these are discussed.

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Documento generato il 06/04/20 alle ore 06:20:24