Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Salivary albumin, total protein, IgA, IgG and IgM concentrations and occurrence of some periodontopathogens in HIV-infected patients: a 2-year follow-up study
Autore:
Mellanen, L; Sorsa, T; Lahdevirta, J; Helenius, M; Kari, K; Meurman, JH;
Indirizzi:
Univ Helsinki, Biomedicum, Helsinki Inst Dent Res Lab, FIN-00014 Helsinki,Finland Univ Helsinki Helsinki Finland FIN-00014 Lab, FIN-00014 Helsinki,Finland Univ Helsinki, Fac Med, FIN-00014 Helsinki, Finland Univ Helsinki Helsinki Finland FIN-00014 ed, FIN-00014 Helsinki, Finland Univ Helsinki, Inst Dent, FIN-00014 Helsinki, Finland Univ Helsinki Helsinki Finland FIN-00014 nt, FIN-00014 Helsinki, Finland Univ Helsinki, Dept Oral & Maxillofacial Dis, FIN-00014 Helsinki, Finland Univ Helsinki Helsinki Finland FIN-00014 is, FIN-00014 Helsinki, Finland Univ Helsinki, Cent Hosp, Helsinki, Finland Univ Helsinki Helsinki Finland v Helsinki, Cent Hosp, Helsinki, Finland
Titolo Testata:
JOURNAL OF ORAL PATHOLOGY & MEDICINE
fascicolo: 9, volume: 30, anno: 2001,
pagine: 553 - 559
SICI:
0904-2512(200110)30:9<553:SATPII>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAPID PCR METHOD; PAROTID-SALIVA; DENTAL PLAQUE; SERUM; ANTIBODIES; SUBCLASSES; RESPONSES; CHILDREN; WHOLE; AIDS;
Keywords:
HIV; polymerase chain reaction; saliva; salivary albumin; salivary immunoglobulins;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Mellanen, L Univ Helsinki, Biomedicum, Helsinki Inst Dent Res Lab, POB 63,Haartmaninkatu 8, FIN-00014 Helsinki, Finland Univ Helsinki POB 63,Haartmaninkatu 8 Helsinki Finland FIN-00014
Citazione:
L. Mellanen et al., "Salivary albumin, total protein, IgA, IgG and IgM concentrations and occurrence of some periodontopathogens in HIV-infected patients: a 2-year follow-up study", J ORAL PATH, 30(9), 2001, pp. 553-559

Abstract

HIV infection reduces oral defensive mechanisms and may affect mucosal integrity. Differences in salivary protein concentrations and periodontopathogenic bacteria were studied in 56 HIV-infected patients with respect to their disease phase. Thirty-three patients were followed up for 2 years. Fifty-three healthy subjects of corresponding age and sex were studied as controls. At baseline, salivary albumin, total protein, IgA, and IgM levels were significantly higher (P <0.05-0.0001) in all phases of HIV infection, exceptthe asymptomatic (ASX) phase, when compared with the control group. IgG levels were significantly increased in all phases except the ASX phase (P <0.05). After 2 years, salivary total protein, IgG, and IgM levels were still higher (P <0.05-0.005) in all HIV phases when compared with the control group (P <0.05-0.005). The albumin level was significantly higher in the ASX phase (P <0.005) and in the AIDS-related complex phase (ARC) (P <0.05), while the increase in IgA level was significant only in the ARC phase (P <0.005). Periodontopathogenic bacteria analyzed by PCR were detected both in the patients and the non-infected, but a statistically significant difference in the carriage percentage between the follow-up lymphadenopathy syndrome phase (LAS) and the control group was found only in Porphyromonas gingivalis (P <0.05) and Bacteroides forsythus (P <0.0001). Thus, HIV infection appeared to cause a significant increase in the studied salivary proteins, suggesting leakage of serum components into the mouth.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 06:18:37