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Titolo:
Magnetic resonance imaging of regional myocardial perfusion in patients with single-vessel coronary artery disease: Quantitative comparison with (201)thallium-SPECT and coronary angiography
Autore:
Keijer, JT; van Rossum, AC; van Eenige, MJ; Bax, JJ; Visser, FC; Teule, JJ; Visser, CA;
Indirizzi:
Free Univ Amsterdam Hosp, Dept Cardiol, NL-1007 MB Amsterdam, Netherlands Free Univ Amsterdam Hosp Amsterdam Netherlands NL-1007 MB m, Netherlands
Titolo Testata:
JOURNAL OF MAGNETIC RESONANCE IMAGING
fascicolo: 6, volume: 11, anno: 2000,
pagine: 607 - 615
SICI:
1053-1807(200006)11:6<607:MRIORM>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-FLOW; COMPUTED-TOMOGRAPHY; CONTRAST AGENT; TRANSIT-TIME; GD-DTPA; DIPYRIDAMOLE STRESS; DISTRIBUTION VOLUME; GADOLINIUM-DTPA; RESERVE; STENOSIS;
Keywords:
myocardial perfusion; coronary artery disease; magnetic resonance imaging; (201)thallium-SPECT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Keijer, JT Free Univ Amsterdam Hosp, Dept Cardiol, Post Box 7057, NL-1007 MB Amsterdam, Netherlands Free Univ Amsterdam Hosp Post Box 7057 AmsterdamNetherlands NL-1007 MB
Citazione:
J.T. Keijer et al., "Magnetic resonance imaging of regional myocardial perfusion in patients with single-vessel coronary artery disease: Quantitative comparison with (201)thallium-SPECT and coronary angiography", J MAGN R I, 11(6), 2000, pp. 607-615

Abstract

The clinical value of magnetic resonance perfusion imaging (Mail) was investigated by quantitative comparison with (201)thallium-single-photon emission computed tomography (Tl-201-SPECT) and quantitative coronary angiography(QCA). Short-axis imaging was performed during dipyridamole administrationin 13 patients with single-vessel coronary artery disease. Using inner andouter contours, the myocardium was divided into 30 contiguous, radial regions. Defining a perfusion defect as a region with less than 90% of maximum Tl-201 intensity, nine patients had a matching perfusion defect, two had nodefect on both Tl-201-SPECT or MRI, and one had a defect on Tl-201-SPECT but not on NM. One patient had a defect on both modalities but with inaccurate localization. Three perfusion parameters were investigated: a) maximum contrast enhancement (MCE); b) slope of the signal intensity versus time curve; and c) inverse mean transit time (1/MTT). The sensitivity and specificity of MCE in the detection of perfusion abnormalities with TI-SPECT as the reference method were 71% and 71%, respectively (slope 77% and 61%, 1/MTT 44% and 70%). Furthermore, correlations were calculated per patient for the entire circumference of the short-axis myocardium. Median correlations wereas follows: MCE 0.92, slope 0.91, and 1/MTT 0.40. Mismatches between Tl-201 defects and defects on MRI resulted in low mean correlations (MCE 0.45, slope 0.46, and 1/MTT 0.26). There was a trend between severity of perfusiondefects on MRI (using MCE) and QCA stenosis area (r = -0.56, P = 0.06). Thus, MRI and Tl-201-SPECT demonstrate fair agreement in the assessment of perfusion defects but show moderate correlation when the entire short-axis myocardium is correlated. J. Magn. Reson. Imaging 2000;11:607-615. (C) 2000 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 06:51:23