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Titolo:
Advances in human cardiac P-31-MR spectroscopy: SLOOP and clinical applications
Autore:
von Kienlin, M; Beer, M; Greiser, A; Hahn, D; Harre, K; Kostler, H; Landschutz, W; Pabst, T; Sandstede, J; Neubauer, S;
Indirizzi:
Univ Wurzburg, Inst Phys, D-8700 Wurzburg, Germany Univ Wurzburg Wurzburg Germany D-8700 nst Phys, D-8700 Wurzburg, Germany
Titolo Testata:
JOURNAL OF MAGNETIC RESONANCE IMAGING
fascicolo: 4, volume: 13, anno: 2001,
pagine: 521 - 527
SICI:
1053-1807(200104)13:4<521:AIHCPS>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAGNETIC-RESONANCE SPECTROSCOPY; ENERGY PHOSPHATE-METABOLISM; CORONARY-ARTERY DISEASE; NMR-SPECTROSCOPY; HUMAN-HEART; PHOSPHORUS METABOLITES; DILATED CARDIOMYOPATHY; MR SPECTROSCOPY; HYPERTROPHIC CARDIOMYOPATHY; MYOCARDIAL-INFARCTION;
Keywords:
cardiac MR spectroscopy; high-energy phosphates; SLOOP; spatial response function; absolute quantitation; dilated cardiomyopathy;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: von Kienlin, M F Hoffmann La Roche Pharma, Bldg 68-05,Grenzacherstr 124, CH-4070 Basel, Switzerland F Hoffmann La Roche Pharma Bldg 68-05,Grenzacherstr 124 Basel Switzerland CH-4070
Citazione:
M. von Kienlin et al., "Advances in human cardiac P-31-MR spectroscopy: SLOOP and clinical applications", J MAGN R I, 13(4), 2001, pp. 521-527

Abstract

Phosphorus magnetic resonance spectroscopy (P-31-MRS) has revealed a lot about the biochemistry of physiological and pathological processes in the heart. Nevertheless, until today, cardiac P-31-MRS has not had any clinical Impact, albeit some pioneering studies demonstrated that P-31-MRS can indeedprovide diagnostic information. In this paper, the development of techniques for human cardiac P-31-MRS over the past decade Is reviewed, and the requirements for a reliable clinical measurement protocol are discussed. Spatial localization with optimal pointspread function (SLOOP) is a new method to achieve spatial localization and absolute quantitation. Its properties are detailed, and preliminary findings in patients with dilated cardiomyopathy or myocardial infarction are presented. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:02:33