Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Long-term frequency tuning of local field potentials in the auditory cortex of the waking guinea pig
Autore:
Galvan, VV; Chen, J; Weinberger, NM;
Indirizzi:
Univ Calif Irvine, Dept Neurobiol & Behav, Qureshey Res Lab CNLM 309, Irvine, CA 92697 USA Univ Calif Irvine Irvine CA USA 92697 Lab CNLM 309, Irvine, CA 92697 USA Univ Calif Irvine, Ctr Neurobiol Learning & Memory, Irvine, CA 92697 USA Univ Calif Irvine Irvine CA USA 92697 ning & Memory, Irvine, CA 92697 USA
Titolo Testata:
JARO
fascicolo: 3, volume: 2, anno: 2001,
pagine: 199 - 215
SICI:
1525-3961(200109)2:3<199:LFTOLF>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
EVOKED-POTENTIALS; RECEPTIVE-FIELDS; SENSORY SYSTEMS; PLASTICITY; ORGANIZATION; MECHANISMS; MEMORY; RAT;
Keywords:
receptive fields; frequency selectivity; evoked potentials; chronic animals; plasticity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Weinberger, NM Univ Calif Irvine, Dept Neurobiol & Behav, Qureshey Res LabCNLM 309, Irvine, CA 92697 USA Univ Calif Irvine Irvine CA USA 92697 Irvine, CA 92697 USA
Citazione:
V.V. Galvan et al., "Long-term frequency tuning of local field potentials in the auditory cortex of the waking guinea pig", JARO, 2(3), 2001, pp. 199-215

Abstract

The goal of our study was to determine the extent of changes in frequency timing in the auditory cortex over weeks. The subjects were awake adult male guinea pigs (n = 8) bearing electrodes chronically implanted in layers IV-VI of primary auditory cortex. Tuning was determined by presenting sequences of pure tone bursts (similar to0.97-41.97 kHz, -20 to 80 dB, 100-ms toneduration, 5-ms rise-fall, 800-ms intertone intervals, 1.5-s intersequence interval) either in 0.5-octave steps (n = 5, 14 probes) or 0.25-octave steps (n = 3, 9 probes) delivered to the ear contralateral to recording sites. Timing curves were determined for local field potentials (LFPs), which weretuned to frequency (negative potential, latency to peak 15-20 ms), repeatedly for up to 27 days (0.5 octave) or 12 days (0.25 octave). Characteristicfrequency (CF), best frequency at 10 and 30 dB above absolute threshold (BF10, BF30), threshold (TH), and bandwidth (10 dB above threshold; BW) were measured. Absolute amplitude often decreased across weeks, necessitating normalization of amplitude. However, there were no significant trends in tuning over days for CF, BF10, or BF30 for either the half- or the quarter-octave group. Both groups exhibited random daily variations in frequency tuning, the quarter-octave group revealing larger variations averaging 0.228, 0.211, and 0.250 octave for CF, BF10, and BF30, respectively. Therefore, frequency tuning in waking animals does not exhibit directional drift over very long periods of time. However, daily tuning variations on the order of 0.20-0.25 octave indicate that the peaks of tuning curves (CF, BF) represent a preferred frequency range rather than a fixed frequency.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 14:28:40