Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Pregnancy-associated cytotoxic lymphoma: A report of 4 cases
Autore:
Kato, M; Ichimura, K; Hayami, Y; Iida, S; Wakita, A; Ueda, R; Nakamura, S;
Indirizzi:
Aichi Canc Ctr, Dept Pathol, Chikusa Ku, Nagoya, Aichi 4648681, Japan Aichi Canc Ctr Nagoya Aichi Japan 4648681 u, Nagoya, Aichi 4648681, Japan Aichi Canc Ctr, Clin Labs, Nagoya, Aichi 4648681, Japan Aichi Canc Ctr Nagoya Aichi Japan 4648681 s, Nagoya, Aichi 4648681, Japan Nagoya City Univ, Sch Med, Dept Internal Med 2, Nagoya, Aichi 467, Japan Nagoya City Univ Nagoya Aichi Japan 467 l Med 2, Nagoya, Aichi 467, Japan
Titolo Testata:
INTERNATIONAL JOURNAL OF HEMATOLOGY
fascicolo: 2, volume: 74, anno: 2001,
pagine: 186 - 192
SICI:
0925-5710(200108)74:2<186:PCLARO>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
T-CELL LYMPHOMAS; DISTINCT CLINICOPATHOLOGICAL ENTITY; NATURAL-KILLER-CELLS; PERFORIN EXPRESSION; LYMPHOCYTES; SPECTRUM; PLACENTA; ORIGIN; SITES; CD56;
Keywords:
pregnancy; TIA-1; granzyme B; T/NK-cell lymphoma; anaplastic large cell lymphoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Nakamura, S Aichi Canc Ctr, Dept Pathol, Chikusa Ku, 1-1 Kanokoden, Nagoya, Aichi 4648681, Japan Aichi Canc Ctr 1-1 Kanokoden Nagoya Aichi Japan 4648681 Japan
Citazione:
M. Kato et al., "Pregnancy-associated cytotoxic lymphoma: A report of 4 cases", INT J HEMAT, 74(2), 2001, pp. 186-192

Abstract

The clinicopathological and biological significance of Hodgkin's disease and non-Hodgkin's lymphoma, which are infrequently encountered in women of childbearing age, remains to be clarified. We recently reviewed 4 cases of non-Hodgkin's lymphoma of the T/natural killer (T/NK)-cell phenotype, all ofwhich were associated with pregnancy and characterized by the expression of the cytotoxic granule-associated proteins T-cell intracellular antigen-1 and/or granzyme B. The 4 cases selected had presented between November 1993and May 1999. The criteria for selection were that the onset of clinical manifestations occurred during pregnancy or within 6 months after delivery. The patients comprised 1 patient with p80/anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALCL), 1 with p80/ALK-negative ALCL, and 2 with peripheral T/NK-cell lymphomas of unspecified type. The diseases followed aggressive clinical courses: 3 patients died within 6.5 monthsafter diagnosis, and only 1 was still alive with the disease 17 months after diagnosis. The diseases appeared to progress rapidly after delivery. Maternal immunity and hormonal changes during pregnancy may be closely relatedto the biological behavior of these unusual tumors. This study is, to the best of our knowledge, the first to address pregnancy-associated cytotoxic lymphoma. (C) 2001 The Japanese Society of Hematology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 22:17:34