Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
What is the relevance of the hope study in general practice?
Autore:
Kennedy, J; Mogensen, CE; Ball, SG; Castaigne, AD; Commerford, PJ; Distiller, L; Fisher, BM; Gonzalez-Jaunatey, J; Nosadini, R; Novials, A; Ostergren, J; Palma-Gamiz, J; Perrone-Filardi, P; Schipperheijn, JJ; Senges, J; Trevisan, R;
Indirizzi:
United Hosp Bergamo, Unit Metab Dis, Bergamo, Italy United Hosp Bergamo Bergamo Italy rgamo, Unit Metab Dis, Bergamo, Italy Ctr Heart, Ludwigshafen, Germany Ctr Heart Ludwigshafen GermanyCtr Heart, Ludwigshafen, Germany Leids Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands Leids Univ LeidenNetherlands ed Ctr, Dept Cardiol, Leiden, Netherlands Univ Naples Federico II, Dept Cardiol, Naples, Italy Univ Naples Federico II Naples Italy co II, Dept Cardiol, Naples, Italy Ramon & Cajal Univ Hosp, Heart & Hypertens Unit, Madrid, Spain Ramon & Cajal Univ Hosp Madrid Spain rt & Hypertens Unit, Madrid, Spain Karolinska Hosp, Dept Med, S-10401 Stockholm, Sweden Karolinska Hosp Stockholm Sweden S-10401 Med, S-10401 Stockholm, Sweden Sarda Farioll Fdn, Barcelona, Spain Sarda Farioll Fdn Barcelona SpainSarda Farioll Fdn, Barcelona, Spain Univ Sassari, Sch Med, I-07100 Sassari, Italy Univ Sassari Sassari ItalyI-07100 sari, Sch Med, I-07100 Sassari, Italy Univ Hosp, Dept Cardiol, Santiago De Compostela, Spain Univ Hosp SantiagoDe Compostela Spain l, Santiago De Compostela, Spain Glasgow Royal Infirm, Glasgow G4 0SF, Lanark, Scotland Glasgow Royal Infirm Glasgow Lanark Scotland G4 0SF 0SF, Lanark, Scotland Ctr Diabet & Endocrinol, Johannesburg, South Africa Ctr Diabet & Endocrinol Johannesburg South Africa nesburg, South Africa Groote Schuur Hosp, Dept Med, Cardiac Clin, ZA-7925 Cape Town, South Africa Groote Schuur Hosp Cape Town South Africa ZA-7925 ape Town, South Africa Hop Henri Mondor, F-94010 Creteil, France Hop Henri Mondor Creteil France F-94010 Mondor, F-94010 Creteil, France Leeds Gen Infirm, Yorkshire Heart Ctr, Leeds, W Yorkshire, England Leeds Gen Infirm Leeds W Yorkshire England , Leeds, W Yorkshire, England Aarhus Kommune Hosp, Med Dept Diabet & Endocrinol M, DK-8000 Aarhus, Denmark Aarhus Kommune Hosp Aarhus Denmark DK-8000 ol M, DK-8000 Aarhus, Denmark
Titolo Testata:
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
fascicolo: 7, volume: 55, anno: 2001,
pagine: 449 - 457
SICI:
1368-5031(200109)55:7<449:WITROT>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONVERTING ENZYME-INHIBITION; LEFT-VENTRICULAR DYSFUNCTION; ACUTE MYOCARDIAL-INFARCTION; HEART-FAILURE; DIABETIC NEPHROPATHY; TRIAL; EVENTS; PREVENTION; RAMIPRIL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Kennedy, J 66 Newlands Rd, Glasgow G43 2JH, Lanark, Scotland 66 Newlands Rd Glasgow Lanark Scotland G43 2JH anark, Scotland
Citazione:
J. Kennedy et al., "What is the relevance of the hope study in general practice?", INT J CL PR, 55(7), 2001, pp. 449-457

Abstract

The unique findings from the HOPE (Heart Outcomes Prevention Evaluation) study strongly support extending the use of the angiotensin-converting enzyme (ACE) inhibitor ramipril as a preventive agent for patients at high risk of cardiovascular events with normal left ventricular function. In addition, ramipril provides significant benefit in diabetic patients. These findings will impact on how ramipril is used in primary care, where ACE inhibitorsare currently underprescribed. Patients reflecting the inclusion criteria of the HOPE study should be considered as suitable candidates for long-termramipril therapy as an addition to their existing drug regimen. Screening should include control of kidney function (by serum creatinine), particularly within the first two weeks of treatment, in addition to regular monitoring of serum potassium. However, the HOPE study shows that ramipril is well tolerated at high doses and over a long treatment period. The effectivenessof therapy should also be regularly reviewed and dose adjustments made where necessary. If concern remains, referral to a specialist - a cardiologistor a diabetologist - may ultimately be necessary.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 00:27:29