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Titolo:
Psychological impact of genetic counselling and testing in women previously diagnosed with breast cancer
Autore:
Randall, J; Butow, P; Kirk, J; Tucker, K;
Indirizzi:
Univ Sydney, Dept Psychol Med, Med Psychol Unit, Sydney, NSW 2006, Australia Univ Sydney Sydney NSW Australia 2006 l Unit, Sydney, NSW 2006, Australia Royal N Shore Hosp, Sydney, NSW, Australia Royal N Shore Hosp Sydney NSW Australia ore Hosp, Sydney, NSW, Australia Westmead Hosp, Dept Med Oncol, Familial Canc Clin, Sydney, NSW, Australia Westmead Hosp Sydney NSW Australia ial Canc Clin, Sydney, NSW, Australia Prince Wales Hosp, Dept Med Oncol, Hereditary Canc Clin, Sydney, NSW, Australia Prince Wales Hosp Sydney NSW Australia Canc Clin, Sydney, NSW, Australia
Titolo Testata:
INTERNAL MEDICINE JOURNAL
fascicolo: 7, volume: 31, anno: 2001,
pagine: 397 - 405
SICI:
1444-0903(200109/10)31:7<397:PIOGCA>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
OVARIAN-CANCER; HEREDITARY BREAST; BRCA1; RISK; SUSCEPTIBILITY; MORBIDITY; FAMILIES; ATTITUDES; MUTATIONS; ANXIETY;
Keywords:
breast cancer; genetic testing; psychological impact;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Butow, P Univ Sydney, Dept Psychol Med, Med Psychol Unit, Blackburn Bldg D06, Sydney, NSW 2006, Australia Univ Sydney Blackburn Bldg D06 Sydney NSW Australia 2006 ustralia
Citazione:
J. Randall et al., "Psychological impact of genetic counselling and testing in women previously diagnosed with breast cancer", INTERN M J, 31(7), 2001, pp. 397-405

Abstract

Background: The recent discovery of susceptibility genes relating to breast cancer, BRCA1 and BRCA2, now allows women with breast cancer and a familyhistory of breast/ovarian cancer to undergo genetic testing to identify a causative germ-line mutation. The present study assessed the psychological status over time of women affected by breast cancer requesting,genetic testing (cases; n=32) compared with matched controls (n=28). Methods: Subjects were recruited through two Sydney-based hospitals. Data were collected via questionnaire and telephone interview at baseline, and 2weeks and 3-6 months following counselling. Results: Genetic test results were not received by the subjects within thestudy period. Cases showed a greater increase in knowledge of cancer genetics following counselling compared with controls, and this was maintained over time. Psychological symptoms remained stable over the study period and there were no differences between groups. Conclusions: Increased knowledge following genetic counselling was not accompanied by an increase in anxiety or depression. Further assessment will be required in the long term to determine the psychological impact of receiving a genetic test result.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 06:26:04