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Titolo:
Antiepileptic drugs for the acute and maintenance treatment of bipolar disorder
Autore:
De Leon, OA;
Indirizzi:
Univ Illinois, Dept Psychiat, Chicago, IL 60612 USA Univ Illinois ChicagoIL USA 60612 , Dept Psychiat, Chicago, IL 60612 USA
Titolo Testata:
HARVARD REVIEW OF PSYCHIATRY
fascicolo: 5, volume: 9, anno: 2001,
pagine: 209 - 222
SICI:
1067-3229(200109/10)9:5<209:ADFTAA>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
MANIC-DEPRESSIVE ILLNESS; DOUBLE-BLIND; LITHIUM-CARBONATE; I DISORDER; ANTIMANIC RESPONSE; MOOD DISORDERS; OPEN-LABEL; CARBAMAZEPINE; EFFICACY; PROPHYLAXIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
100
Recensione:
Indirizzi per estratti:
Indirizzo: De Leon, OA Univ Illinois, Dept Psychiat, 912 S Wood St,M-C 913, Chicago, IL 60612 USA Univ Illinois 912 S Wood St,M-C 913 Chicago IL USA 60612 2 USA
Citazione:
O.A. De Leon, "Antiepileptic drugs for the acute and maintenance treatment of bipolar disorder", HARV R PSYC, 9(5), 2001, pp. 209-222

Abstract

Both traditional and newer antiepileptic drugs have been considered for the acute and maintenance treatment of bipolar disorder. Although the psychotropic actions of these compounds have long been recognized, their specific mood-stabilizing properties have become evident only relatively recently. Carbamazepine and valproate are the antiepileptics most thoroughly studied for the treatment of bipolar disorder, but trials of the newer compounds such as lamotrigine, gabapentin, topiramate, and tiagabine have also begun to emerge. This article reviews the published research (including controlled trials, outcome reports, case series, and anecdotal observations) relevant to the efficacy of these agents in the acute and maintenance treatment of bipolar disorder. It also reviews the available information regarding clinical predictors of response. Despite considerable interest in these drugs, data are still limited. Comparison of clinical responses to the various mood stabilizers and determination of their mechanisms of action could help to improve treatment for bipolar disorder.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 13:31:27