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Titolo:
Neurotransmitters, temperament and social functioning
Autore:
Bond, AJ;
Indirizzi:
Univ London Kings Coll, Sect Clin Psychopharmacol, Inst Clin Psychopharmacol, London SE5 8AF, England Univ London Kings Coll London England SE5 8AFl, London SE5 8AF, England
Titolo Testata:
EUROPEAN NEUROPSYCHOPHARMACOLOGY
fascicolo: 4, volume: 11, anno: 2001,
pagine: 261 - 274
SICI:
0924-977X(200108)11:4<261:NTASF>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRIDIMENSIONAL PERSONALITY QUESTIONNAIRE; SEROTONIN TRANSPORTER GENE; ANXIETY-RELATED TRAITS; EXON-III POLYMORPHISM; RECEPTOR D4 DRD4; CATECHOL O-METHYLTRANSFERASE; MAJOR DEPRESSIVE DISORDER; REPEATED D-AMPHETAMINE; NOVELTY SEEKING; CHARACTER INVENTORY;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
129
Recensione:
Indirizzi per estratti:
Indirizzo: Bond, AJ Univ London Kings Coll, Sect Clin Psychopharmacol, Inst Clin Psychopharmacol, De Crespigny Pk, London SE5 8AF, England Univ London Kings Coll De Crespigny Pk London England SE5 8AF nd
Citazione:
A.J. Bond, "Neurotransmitters, temperament and social functioning", EUR NEUROPS, 11(4), 2001, pp. 261-274

Abstract

Dimensional models can be usefully employed to describe both normal and disordered personality. Studies in molecular genetics, receptor binding, peripheral monoamines and pharmacological challenges have investigated the neurochemical basis of personality. Substantial evidence now exists to support a psychobiological model but the specificity of Cloninger's theory has not always been confirmed. Clinical studies have shown both temperament and character dimensions to improve with pharmacological treatment especially in treatment responders. Some personality changes are found to be independent of clinical effects and even to occur in normal subjects. Models of personality can help in predicting treatment outcome but individual dimensions may not be useful. It is hypothesised that social adaptation is related to the character dimensions and different sources of evidence link these to serotonergic actions. However, recent clinical studies have shown a specific effect of noradrenaline on self-perception and social motivation. Drugs with specific actions on different neurotransmitters may exert a distinctive pattern of effects on personality and social behaviour. (C) 2001 Elsevier Science BY. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 22:00:42