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Titolo:
Surgical removal of subfoveal choroidal neovascularization: visual outcomeand prognostic value of fluorescein angiography and optical coherence tomography
Autore:
Brindeau, C; Glacet-Bernard, A; Coscas, F; Mimoun, G; Boukhli, L; Coscas, G; Soubrane, G;
Indirizzi:
Univ Paris 12, Ctr Hosp Intercommunal, Dept Ophthalmol, Assistance Publ Hop Paris, F-94000 Creteil, France Univ Paris 12 Creteil France F-94000 Hop Paris, F-94000 Creteil, France Univ Paris 12, Hop Henri Mondor, Dept Ophthalmol, Assistance Publ Hop Paris, F-94000 Creteil, France Univ Paris 12 Creteil France F-94000 Hop Paris, F-94000 Creteil, France
Titolo Testata:
EUROPEAN JOURNAL OF OPHTHALMOLOGY
fascicolo: 3, volume: 11, anno: 2001,
pagine: 287 - 295
SICI:
1120-6721(200107/09)11:3<287:SROSCN>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRESUMED OCULAR HISTOPLASMOSIS; MACULAR DEGENERATION; SUBMACULAR SURGERY; MEMBRANES; EXCISION; MYOPIA; TRIAL;
Keywords:
choroidal neovascularization; macular surgery; angiography; optical coherence tomography; CNV recurrence;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Soubrane, G Univ Paris 12, Ctr Hosp Intercommunal, Dept Ophthalmol, Assistance Publ Hop Paris, 40 Ave Verdun, F-94000 Creteil, France Univ Paris 12 40 Ave Verdun Creteil France F-94000 il, France
Citazione:
C. Brindeau et al., "Surgical removal of subfoveal choroidal neovascularization: visual outcomeand prognostic value of fluorescein angiography and optical coherence tomography", EUR J OPTHA, 11(3), 2001, pp. 287-295

Abstract

PURPOSE. To study the functional results of macular surgery and determine pre-operative features associated with better final visual outcome. METHODS. Forty-two consecutive patients underwent surgical removal of subfoveal choroidal neovascularization (CNV), related to age-related macular degeneration (AMD) in 8 eyes, degenerative myopia in 14 eyes, multifocal choroiditis (MFC) In 10 eyes, idiopathic CNV in 6 eyes and other etiologies in 4 eyes. Mean age was 49 years. Pre-operative visual acuity (VA) was 20/200 or less in 30 eyes (71.4%) and never better than 20/40. Fluorescein angiography was analyzed before and after surgery. Pre-operative optical coherencetomographs (OCT) were studied in a masked fashion. Mean follow-up was 12 months (range 4-48 months). RESULTS. Final VA was 20/200 or less in 25 eyes (60%). According to the CNV etiology, the percentage were 87.5%, 80%, 57.1% and 20% respectively in eyes with AMD, MFC, high myopia, and idiopathic or other diseases. Post-operative VA improved in 21 eyes (50%) but subsequently declined in 7% by the final examination. Patients younger than 50 years had better functional results (p=0.006). Lack of retinal pigment epithelium (RPE) changes on pre-operative angiography was correlated with good visual outcome (p <0.001). The OCT study confirmed some features already described and showed some different CNV patterns: above and usually separated from the RPE, below and not separated from the RPE, and ungradable. Eyes with the first OCT pattern had the best visual outcome. Main complications included 4 (10%) retinal detachments and 9 (21%) recurrences. OCT was also useful to confirm CNV recurrencespost-operatively. CONCLUSIONS. CNV surgical excision results vary depending on the underlying disease, the RPE and choriocapillaris function, and the features observedon pre-operative OCT images.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 18:44:33