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Titolo:
Trabeculectomy with and without mitomycin-C in a black African population
Autore:
Mwanza, JCK; Kabasele, PM;
Indirizzi:
Univ Hosp Kinshasa, Dept Ophthalmol, Kinshasa, Zaire Univ Hosp Kinshasa Kinshasa Zaire asa, Dept Ophthalmol, Kinshasa, Zaire Bondeko Clin, Dept Ophthalmol, Kinshasa, Zaire Bondeko Clin Kinshasa Zaire deko Clin, Dept Ophthalmol, Kinshasa, Zaire
Titolo Testata:
EUROPEAN JOURNAL OF OPHTHALMOLOGY
fascicolo: 3, volume: 11, anno: 2001,
pagine: 261 - 263
SICI:
1120-6721(200107/09)11:3<261:TWAWMI>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADJUNCTIVE MITOMYCIN; ANTIFIBROTIC AGENTS; YOUNG-PATIENTS; LONG-TERM; SUBCONJUNCTIVAL; GLAUCOMA; RISK;
Keywords:
trabeculectomy; mitomycin-C; black African;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Mwanza, JCK Univ Bergen, Haukeland Hosp, Ctr Int Hlth, Armauer Hansen Bldg, N-5021 Bergen, Norway Univ Bergen Armauer Hansen Bldg Bergen Norway N-5021 , Norway
Citazione:
J.C.K. Mwanza e P.M. Kabasele, "Trabeculectomy with and without mitomycin-C in a black African population", EUR J OPTHA, 11(3), 2001, pp. 261-263

Abstract

PURPOSE. To evaluate the beneficial effects of intraoperative application of mitomycin-C during trabeculectomy in a black African population in Congo-Kinshasa. METHODS. A prospective randomized study in 22 eyes (11 patients) with open-angle glaucoma. All patients underwent trabeculectomy with application of mitomycin-C (0.4 mg/ml for 2.5 min) under the scleral flap in the right eyeand trabeculectomy alone in the left eye. Assessment of the clinical outcome included intraocular pressure, visual acuity, visual field and complications. The follow-up was 20 months. Success of the filtering surgery was defined as a final IOP of 21 mmHg or lower without antiglaucoma medications and no further glaucoma surgery necessary. RESULTS. The success rate of trabeculectomy was 81.8% in eyes treated withmitomycin-C compared with 63.6% in eyes not receiving this drug. Rates of intraocular pressure reduction were 57.9% and 42.9% respectively. Complications occured in 36.3% of the eyes managed with mitomycin-C against 9% in the control eyes. CONCLUSIONS. Mitomycin-C, as adjunctive treatment during trabeculectomy inblack Africans, offers great benefit in lowering IOP, but with a substantial high risk of complications. These data need to be confirmed by further studies in this population.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 06:26:56