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Titolo:
Intranasal corticosteroids for allergic rhinitis - Superior relief?
Autore:
Nielsen, LP; Mygind, N; Dahl, R;
Indirizzi:
Aarhus Univ, Dept Clin Pharmacol, DK-8000 Aarhus, Denmark Aarhus Univ Aarhus Denmark DK-8000 in Pharmacol, DK-8000 Aarhus, Denmark Aarhus Univ Hosp, Dept Resp Dis, DK-8000 Aarhus, Denmark Aarhus Univ HospAarhus Denmark DK-8000 esp Dis, DK-8000 Aarhus, Denmark
Titolo Testata:
DRUGS
fascicolo: 11, volume: 61, anno: 2001,
pagine: 1563 - 1579
SICI:
0012-6667(2001)61:11<1563:ICFAR->2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
AQUEOUS NASAL SPRAY; QUALITY-OF-LIFE; 200 MU-G; DAILY FLUTICASONE PROPIONATE; BECLOMETHASONE DIPROPIONATE; DOUBLE-BLIND; PERENNIAL RHINITIS; HAY-FEVER; MOMETASONE FUROATE; PHARMACOLOGICAL PROPERTIES;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
200
Recensione:
Indirizzi per estratti:
Indirizzo: Nielsen, LP Aarhus Univ, Dept Clin Pharmacol, Bartholin Bldg, DK-8000 Aarhus, Denmark Aarhus Univ Bartholin Bldg Aarhus Denmark DK-8000 us, Denmark
Citazione:
L.P. Nielsen et al., "Intranasal corticosteroids for allergic rhinitis - Superior relief?", DRUGS, 61(11), 2001, pp. 1563-1579

Abstract

Whether first-line pharmacological treatment of allergic rhinitis should be antihistamines or intranasal corticosteroids has been discussed for several years. First-generation antihistamines are rarely used in the treatment of allergic rhinitis, mainly because of sedative and anticholinergic adverse effects. On the basis of clinical evidence of efficacy, no second-generation antihistamine seems preferable to another. Similarly, comparisons of topical and oral antihistamines have been unable to demonstrate superior efficacy for one method of administration over the other. Current data documents no striking differences in efficacy and safety parameters between intranasal corticosteroids. When the efficacy of antihistamines and intranasal corticosteroids are compared in patients with allergic rhinitis, present data favours intranasal corticosteroids. Interestingly, data do not show antihistamines as superior for the treatment of conjunctivitis. Safety data from comparative studies in patients with allergic rhinitis do not indicate differences between antihistamines and intranasal corti-costeroids. Combining antihistamines and intranasal corticosteroids in the treatment of allergic rhinitis does not provide any additional effect to intranasal corticosteroids alone. On the basisof current data, intranasal corticosteroids seem to offer superior relief in allergic rhinitis than antihistamines.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 23:53:11