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Titolo:
Mortality and causes of death in the WHO multinational study of vascular disease in diabetes
Autore:
Morrish, NJ; Wang, SL; Stevens, LK; Fuller, JH; Keen, H;
Indirizzi:
Univ Coll London, Dept Epidemiol & Publ Hlth, EURODIAB, London WC1E 6BT, England Univ Coll London London England WC1E 6BT ODIAB, London WC1E 6BT, England Bedford Hosp, N Bedfordshire Diabet Ctr, Bedford, England Bedford Hosp Bedford England Bedfordshire Diabet Ctr, Bedford, England Guys Hosp, Metab Med Unit, London SE1 9RT, England Guys Hosp London England SE1 9RT Metab Med Unit, London SE1 9RT, England
Titolo Testata:
DIABETOLOGIA
, volume: 44, anno: 2001, supplemento:, 2
pagine: S14 - S21
SICI:
0012-186X(200109)44:<S14:MACODI>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIOVASCULAR MORTALITY; RISK-FACTORS; MELLITUS; SURVIVAL; AGE; PROTEINURIA; POPULATION; PROGNOSIS; IMPACT;
Keywords:
mortality; Type I (insulin-dependent) diabetes mellitus; Type II (non-insulin-dependent) diabetes mellitus; standardised mortality ratio; cardiovascular disease; renal disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Fuller, JH Univ Coll London, Dept Epidemiol & Publ Hlth, EURODIAB, 1-19 Torrington Pl, London WC1E 6BT, England Univ Coll London 1-19 Torrington Pl London England WC1E 6BT nd
Citazione:
N.J. Morrish et al., "Mortality and causes of death in the WHO multinational study of vascular disease in diabetes", DIABETOLOG, 44, 2001, pp. S14-S21

Abstract

Aims/hypothesis. We aimed to examine the mortality rates, excess mortalityand causes of death in diabetic patients from ten centres throughout the world. Methods. A mortality follow-up of 4713 WHO Multinational Study of VascularDisease in Diabetes (WHO MSVDD) participants from ten centres was carried out, causes of death were ascertained and age-adjusted mortality rates werecalculated by centre, sex and type of diabetes. Excess mortality, comparedwith the background population, was assessed in terms of standardised mortality ratios (SMRs) for each of the 10 cohorts. Results. Cardiovascular disease was the most common underlying cause of death, accounting for 44% of deaths in Type I (insulin-dependent) diabetes mellitus and 52% of deaths in Type II (non-insulin-dependent) diabetes mellitus. Renal disease accounted for 21% of deaths in Type I diabetes and 11% inType II diabetes. For Type I diabetes, all-cause mortality rates were highest in Berlin men and Warsaw women, and lowest in London men and Zagreb women. For Type II diabetes, rates were highest in Warsaw men and Oklahoma women and lowest in Tokyo men and women. Age adjusted mortality rates and SMRswere generally higher in patients with Type I diabetes compared with thosewith Type II diabetes. Men and women in the Tokyo cohort had a very low excess mortality when compared with the background population. Conclusion/interpretation. This study confirms the importance of cardiovascular disease as the major cause of death in people with both types of diabetes. The low excess mortality in the Japanese cohort could have implications for the possible reduction of the burden of mortality associated with diabetes in other parts of the world.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 09:17:13