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Titolo:
Systemic lupus erythematosus and antiphospholipid syndrome in children andadolescents
Autore:
Lee, T; von Scheven, E; Sandborg, C;
Indirizzi:
Stanford Univ, Med Ctr, Dept Pediat, Stanford, CA 94305 USA Stanford UnivStanford CA USA 94305 , Dept Pediat, Stanford, CA 94305 USA Univ Calif San Francisco, Dept Pediat, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA
Titolo Testata:
CURRENT OPINION IN RHEUMATOLOGY
fascicolo: 5, volume: 13, anno: 2001,
pagine: 415 - 421
SICI:
1040-8711(200109)13:5<415:SLEAAS>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRESENTING CLINICAL-FEATURE; JUVENILE CHRONIC ARTHRITIS; ANTICARDIOLIPIN ANTIBODIES; INTRAVENOUS METHYLPREDNISOLONE; CARDIOVASCULAR-DISEASE; COGNITIVE IMPAIRMENT; ARTERIAL THROMBOSIS; PEDIATRIC-PATIENTS; RISK-FACTORS; CHILDHOOD;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
98
Recensione:
Indirizzi per estratti:
Indirizzo: Sandborg, C Stanford Univ, Med Ctr, Dept Pediat, Room G310,300 Pasteur Dr,Stanford, CA 94305 USA Stanford Univ Room G310,300 Pasteur Dr Stanford CA USA 94305 A
Citazione:
T. Lee et al., "Systemic lupus erythematosus and antiphospholipid syndrome in children andadolescents", CURR OP RH, 13(5), 2001, pp. 415-421

Abstract

Systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS) canbe associated with significant morbidity in children and adolescents. Renal involvement in SLE appears to be more severe and more frequent in the pediatric age group, with the major predictors for poor outcome being the severity of histopathologic lesions, severity of renal impairment at diagnosis,and hypertension. In addition to currently recognized cardiovascular and pulmonary involvement, accelerated atherosclerosis is of increasing concern in young individuals with SLE, because of both disease effects and medication usage. Neuropsychiatric SLE seen in childhood ranges from subtle cognitive dysfunction to severe central nervous system involvement; however, thereis controversy over the value of different diagnostic studies. APS in children may be associated with SLE, idiopathic, or associated with viral infections. Systemic anticoagulation is recommended for patients with thromboticevents, but long-term management has not been well studied in children. (C) 2001 Lippincott Williams & Wilkins, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 19:07:47