Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Pituitary adenoma with galactorrhea in an adult male cynomolgus macaque (Macaca fascicularis)
Autore:
Daviau, JS; Trupkiewicz, JG;
Indirizzi:
Thomas Jefferson Univ, Lab Anim Serv, Philadelphia, PA 19107 USA Thomas Jefferson Univ Philadelphia PA USA 19107 hiladelphia, PA 19107 USA Philadelphia Zoo, Philadelphia, PA 19104 USA Philadelphia Zoo Philadelphia PA USA 19104 oo, Philadelphia, PA 19104 USA
Titolo Testata:
CONTEMPORARY TOPICS IN LABORATORY ANIMAL SCIENCE
fascicolo: 5, volume: 40, anno: 2001,
pagine: 57 - 59
SICI:
1060-0558(200109)40:5<57:PAWGIA>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
CUSHINGS-DISEASE; NONHUMAN-PRIMATES; DIABETES-MELLITUS; RHESUS-MONKEY; TESTOSTERONE; PROLACTIN; MULATTA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Daviau, JS Thomas Jefferson Univ, Lab Anim Serv, 233 S 10th St, Philadelphia, PA 19107 USA Thomas Jefferson Univ 233 S 10th St Philadelphia PA USA 19107 A
Citazione:
J.S. Daviau e J.G. Trupkiewicz, "Pituitary adenoma with galactorrhea in an adult male cynomolgus macaque (Macaca fascicularis)", CONT T LAB, 40(5), 2001, pp. 57-59

Abstract

Although endocrinopathies in many animal species are well documented, an adult, male, wild-caught cynomolgus macaque (Macaca fascicularis) presented an interesting diagnostic challenge. Previous physical examinations had been unremarkable with the exception of a heart murmur. The animal presented with ulcerative dermatitis in the dorsal cervical area, and physical exam revealed white material around the nipples. A white milky substance could be expressed bilaterally from the nipples. Hematologic, serologic, and urine samples revealed glucosuria, ketonuria, and hyperglycemia. Further diagnostic testing confirmed persistent hyperglycemia and revealed elevated serum prolactin and cortisol levels. During subsequent imaging studies, the animal underwent cardiac arrest and was euthanized. Gross necropsy findings included an enlarged pituitary gland. A prolactin-secreting pituitary adenoma wasconfirmed on histopathology. In light of the results of serum biochemical analyses, the additional diagnosis of type II non-insulin-dependent diabetes mellitus was made. This case represents the first documented antemortem diagnosis of a prolactin-secreting pituitary tumor in a cynomolgus macaque.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 19:17:05