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Titolo:
Substance abuse in bipolar disorder
Autore:
Cassidy, F; Ahearn, EP; Carroll, BJ;
Indirizzi:
Duke Univ, Duke Umstead Bipolar Disorders Program, Durham, NC USA Duke Univ Durham NC USA mstead Bipolar Disorders Program, Durham, NC USA Pacific Behav Res Fdn, Carmel, CA USA Pacific Behav Res Fdn Carmel CA USA acific Behav Res Fdn, Carmel, CA USA
Titolo Testata:
BIPOLAR DISORDERS
fascicolo: 4, volume: 3, anno: 2001,
pagine: 181 - 188
SICI:
1398-5647(200108)3:4<181:SAIBD>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
MANIC-DEPRESSIVE ILLNESS; DRUG-ABUSE; 1ST HOSPITALIZATION; MENTAL-DISORDERS; UNITED-STATES; MIXED MANIA; COMORBIDITY; SCHIZOPHRENIA; SYMPTOMS; ALCOHOL;
Keywords:
alcohol abuse; bipolar disorder; course; mixed mania; sex; substance abuse;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Cassidy, F Duke Univ, Med Ctr, Box 34143, Durham, NC 27710 USA Duke Univ Box 34143 Durham NC USA 27710 3, Durham, NC 27710 USA
Citazione:
F. Cassidy et al., "Substance abuse in bipolar disorder", BIPOL DIS, 3(4), 2001, pp. 181-188

Abstract

Background. High rates of substance abuse have been reported in the general population, with males more often affected than females. Although high rates of substance abuse have also been reported in bipolar patients, the relationship between substance abuse and bipolar disorder has not been well characterized. Methods: Substance abuse histories were obtained in 392 patients hospitalized for manic or mixed episodes of bipolar disorder and rates of current and lifetime abuse calculated. Analyses comparing sex, subtype (manic vs. mixed) and clinical history variables were conducted. Results: Rates of lifetime substance abuse were high for both alcohol (48.5%) and drugs (43.9%). Nearly 60% of the cohort had a history of some lifetime substance abuse. Males had higher rates of abuse than females, but no differences in substance abuse were observed between subjects in manic and mixed bipolar states. Rates of active substance abuse were lower in older age cohorts. Subjects with a comorbid diagnosis of lifetime substance abuse had more psychiatric hospitalizations. Conclusions: Substance abuse is a major comorbidity in bipolar patients. Although rates decrease in older age groups, substance abuse is still present at clinically important rates in the elderly. Bipolar patients with comorbid substance abuse may have a more severe course. These data underscore the significance of recognition and treatment of substance abuse in bipolar disorder patients.

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Documento generato il 18/01/20 alle ore 02:43:34