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Titolo:
Assessment of myocardial infarction in humans with Na-23 MR imaging: Comparison with cine MR imaging and delayed contrast enhancement
Autore:
Sandstede, JJW; Pabst, T; Beer, M; Lipke, C; Baurle, K; Butter, F; Harre, K; Kenn, W; Voelker, W; Neubauer, S; Hahn, D;
Indirizzi:
Univ Wurzburg, Dept Radiol, D-97070 Wurzburg, Germany Univ Wurzburg Wurzburg Germany D-97070 Radiol, D-97070 Wurzburg, Germany Univ Wurzburg, Dept Internal Med, D-97070 Wurzburg, Germany Univ WurzburgWurzburg Germany D-97070 al Med, D-97070 Wurzburg, Germany Univ Oxford, Dept Cardiovasc Med, Oxford OX1 2JD, England Univ Oxford Oxford England OX1 2JD rdiovasc Med, Oxford OX1 2JD, England
Titolo Testata:
RADIOLOGY
fascicolo: 1, volume: 221, anno: 2001,
pagine: 222 - 228
SICI:
0033-8419(200110)221:1<222:AOMIIH>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
MICROVASCULAR OBSTRUCTION; DYSFUNCTIONAL MYOCARDIUM; VIABILITY; SODIUM; SIZE; REPERFUSION; DISEASE; IMAGES; INJURY;
Keywords:
myocardium, infarction; myocardium, MR; magnetic resonance (MR), sodium studies;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Sandstede, JJW Univ Wurzburg, Dept Radiol, Klin Str 8, D-97070 Wurzburg, Germany Univ Wurzburg Klin Str 8 Wurzburg Germany D-97070 Germany
Citazione:
J.J.W. Sandstede et al., "Assessment of myocardial infarction in humans with Na-23 MR imaging: Comparison with cine MR imaging and delayed contrast enhancement", RADIOLOGY, 221(1), 2001, pp. 222-228

Abstract

PURPOSE: To demonstrate the feasibility of sodium 23 (Na-23) magnetic resonance (MR) imaging for assessment of subacute and chronic myocardial infarction and compare with cine, late enhancement, and T2-weighted imaging. MATERIALS AND METHODS: Thirty patients underwent MR imaging 8 days +/- 4 (subacute, n = 15) or more than 6 months (chronic, n = 15) after myocardial infarction by using a Na-23 surface coil with a double angulated electrocardiogram-triggered three-dimensional gradient-echo sequence at 1.5 T. In addition, cine, inversion-recovery gradient-echo, and, in the subacute group, T2-weighted images (n = 9) were obtained. Myocardial infarction mass was depicted as elevated signal intensity or wall motion abnormalities and expressed as a percentage of total left ventricular mass for all modalities. Correlations were tested with correlation coefficients. RESULTS: All patients after subacute infarction and 12 of 15 patients withchronic infarction had an area of elevated Na-23 signal intensity that significantly correlated with wall motion abnormalities (subacute; r = 0.96, P< .001, and chronic; r = 0.9, P < .001); three patients had no wall motionabnormalities or elevated Na-23 signal intensity. Only 10 patients in the subacute and nine in the chronic group revealed late enhancement; significant correlation with Na-23 MR imaging occurred only in subacute group (r = 0.68, P < .05). Myocardial edema in subacute infarction correlated (r = 0.71, P < .05) with areas of elevated Na-23 signal intensity but was extensively larger. CONCLUSION : Na-23 MR imaging demonstrates dysfunctional myocardium causedby subacute and chronic myocardial infarction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 20:46:08