Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Who are we blinding? A systematic review of blinded clinical trials
Autore:
Park, J; White, AR; Stevinson, C; Ernst, E;
Indirizzi:
Univ Exeter, Postgrad Med Sch & Hlth Sci, Dept Complementary Med, Exeter EX2 4NT, Devon, England Univ Exeter Exeter Devon England EX2 4NT , Exeter EX2 4NT, Devon, England
Titolo Testata:
PERFUSION
fascicolo: 8, volume: 14, anno: 2001,
pagine: 296 -
SICI:
0935-0020(200108)14:8<296:WAWBAS>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
RANDOMIZED CONTROLLED TRIAL; TRANSCRANIAL MAGNETIC STIMULATION; OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY; LAPAROSCOPIC NISSEN FUNDOPLICATION; CATHETER-BASED RADIOTHERAPY; CONGESTIVE-HEART-FAILURE; POSITIVE AIRWAY PRESSURE; CARPAL-TUNNEL SYNDROME; LOW-BACK-PAIN; SINGLE-BLIND;
Keywords:
double blind; single blind; terminology; randomised clinical trials;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
82
Recensione:
Indirizzi per estratti:
Indirizzo: Park, J Univ Exeter, Postgrad Med Sch & Hlth Sci, Dept Complementary Med, 25 Victoria Pk Rd, Exeter EX2 4NT, Devon, England Univ Exeter 25 Victoria Pk Rd Exeter Devon England EX2 4NT England
Citazione:
J. Park et al., "Who are we blinding? A systematic review of blinded clinical trials", PERFUSION, 14(8), 2001, pp. 296

Abstract

Background: The terms much greater than double blind (masked)much less than and much greater than single blind much less than are often used to mean different things in reports of blinded clinical trials of non-pharmaceutical interventions. Objective: To investigate the discordance in usage of the terms much greater than double blindo and much greater than single blind much less than in non-pharmaceutical clinical trials. Methods: A computerized literature search was conducted in Medline (1997 to April 2000). journals were chosen that deemed likely to contain non-pharmaceutical RCTs and that had the highest Impact Factor. Search terms used were much greater than double-blind much less than and much greater than single blindo. Articles were included in the review if they reported prospective randomised controlled trials of non-pharmaceutical interventions using the term much greater than double blind much less than or much greater than single blind much less than. Assessment of the blinding was performed independently by two authors, who recorded the presence of details of the blinding of four possible parties: subjects (participants, patients), therapists (intervention givers), assessors (evaluators), and data analysts. The consistency in the use of terminology in eachjournal was also investigated. No assumptions were made, but specific confirmatory statements by the authors were sought in the text. Results. A total of 48 articles from 17 journals were included for data extraction, 25 in the double blind, and 23 in the single blind category. The letters S, A, T, D represents subject (S), assessor (A), therapist (T), data analyst (D) blinding. In the studies labeled as much greater than double blindo, blinding was performed as follows: two used SATD blinding; five blinded SAT; seven SAD; nine SA; two S only; no study was not blinded in at least one respect. In the studies labeled much greater than single blind muchless than, one study blinded SAD; five SA; one ST; two AD; one S; eleven A; one D; no study blinded T; and one study used no blinding at all. Different types of blinding within identically labeled studies and discordant terminology using same blinding design was found. In five journals, the use of much greater than double blind much less than and much greater than single blindo was inconsistent. Conclusion: There is clear discordance in the usage of the terms much greater than double blind much less than and much greater than single blind much less than in the reports of non- pharmaceutical randomised controlled trials published in high quality journals. We suggest that reports should expressly state which parties were blinded.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 04:41:42